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Percodan

oxycodone / aspirin
Used for Pain
Used for Pain

Oxycodone / aspirin is a combination medication that's used to treat severe pain. It's a controlled substance because it has a high risk of dependency, misuse, and overdose, even at recommended doses. It's no longer available in the United States because it was discontinued.

Reviewed by:
reviewer
Robert Chad Hakim, PharmD, BCCCP
reviewer
Kristianne Hannemann, PharmD
Last reviewed on February 5, 2023
BasicsFAQsInteractionsReferencesPricesMedicare
Oxycodone / aspirin is a controlled substance, which means that it's more likely to be misused or cause dependence. There are federal and state laws that limit the amount of medication that can be prescribed or dispensed within a certain period of time.
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What is Oxycodone / aspirin?

What is Oxycodone / aspirin used for?

  • Severe pain not relieved by non-opioid pain medications

How Oxycodone / aspirin works

Are you looking for information on oxycodone / acetaminophen (Percocet) instead?

Drug Facts

Common BrandsPercodan (brand no longer available)
Drug ClassOpioid / NSAID
Controlled Substance ClassificationSchedule II
Generic StatusNo lower-cost generic available
AvailabilityDiscontinued
faqs

Frequently asked questions about Oxycodone / aspirin

What is oxycodone / aspirin?
Oxycodone / aspirin is a combination of two pain relievers. Oxycodone is an opioid that attaches to specific pain receptors in the body, which helps to treat pain. Aspirin is a nonsteroidal anti-inflammatory drug (NSAID). It blocks proteins in your body that cause inflammation (swelling), which can lower pain. Oxycodone / aspirin treats severe pain not relieved by non-opioid pain medications.
Is oxycodone / aspirin still available?
No, oxycodone / aspirin has been discontinued and is no longer available in the United States. It's not clear why oxycodone / aspirin has been discontinued.
What medications can I use in place of oxycodone / aspirin?
There are many pain medications available to treat severe pain. Your provider can help guide you to the best treatment options based on your individual health conditions.
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interactions

Interactions between Oxycodone / aspirin and other drugs

Oxycodone / aspirin may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Oxycodone / aspirin. Please note that only the generic name of each medication is listed below.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

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References

Best studies we found

Endo Pharmaceuticals Inc. (2021). Percodan® (axycodone and aspirin tablets, USP) [package insert]. U.S. Food and Drug Administration.

GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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