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Osphena (ospemifene) is used to treat vaginal dryness and painful sexual intercourse due to menopause. There are currently no generic alternatives for Osphena.
GoodRx has partnered with InsideRx and Duchesnay USA to reduce the price for this prescription. Check our savings tips for co-pay cards, assistance programs, and other ways to reduce your cost. Osphena is covered by some Medicare and insurance plans.
Get Osphena for as low as $205.20, which is 77% off the average retail price of $899.85 for the most common version, by using a GoodRx coupon.

| Dosage | Quantity | Retail price | GoodRx price |
|---|
| 60mg | 90 tablets | $847.43 | $205.20 |
GoodRx coupon prices last updated on 05/02/26.