Tri-Sprintec is a type of combined oral contraceptive (COC), or birth control, that's taken by mouth every day to prevent pregnancy. It's a triphasic birth control, meaning it has three different phases of hormones that tries to mimic the rise and fall of hormones in the menstrual cycle. Some people find triphasic birth controls, like Tri-Sprintec more complicated to take, especially if they need to make up for a missed dose.
Tri-Sprintec is a combination medication that contains two hormones, norgestimate (a progestin) and ethinyl estradiol (an estrogen). Both hormones work together to prevent pregnancy by:
Tri-Sprintec can also be used to treat acne. This medication helps with acne by lowering the amount of testosterone (a hormone) in your body. This leads to less oil production and less clogging of the pores of the skin.
The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Contact your healthcare provider immediately if you experience any of the following.
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Incidence not known
Absent, missed, or irregular menstrual periods
change in vision
changes in skin color
chest pain or discomfort
chills
clay-colored stools
dark urine
dizziness or lightheadedness
fainting
headache
hives or welts
itching skin
large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
loss of appetite
medium to heavy, irregular vaginal bleeding between regular monthly periods, which may require the use of a pad or a tampon
pain or discomfort in the arms, jaw, back, or neck
pain, tenderness, or swelling of the foot or leg
pains in the chest, groin, or legs, especially in the calves of the legs
pounding in the ears
rash
redness of the skin
severe headaches of sudden onset
slow or fast heartbeat
stomach pain
sudden loss of coordination or slurred speech
sudden troubled breathing
sweating
unusual tiredness or weakness
vomiting
vomiting of blood
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Incidence not known
blotchy spots on the exposed skin
breast enlargement or tenderness
discouragement
feeling sad or empty
irritability
itching of the vagina or outside the genitals
loss of interest or pleasure
pain during sexual intercourse
stomach cramps
thick, white curd-like vaginal discharge without odor or with mild odor
tiredness
trouble concentrating
trouble sleeping
trouble wearing contact lenses
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Tri-Sprintec is called a triphasic birth control because it contains three different phases of hormone levels throughout the first three weeks. This is designed to mimic your natural hormone levels more closely compared with birth control pills that contain the same doses of hormones in all of the active pills. Ask your provider if you're not sure whether a triphasic birth control is right for you.
Tri-Sprintec is made up of four different sets of colored pills, each with different dosages of hormones (or no hormones in the case of the inactive pills). As mentioned above, Tri-Sprintec has three different combinations of hormone levels. The first three weeks are "active" pills, which means that they contain hormones. The fourth week is made up of "inactive" pills, which don't have hormones. It's important for you to take the tablets in the correct order so your body can follow the appropriate hormone levels.
Tri-Sprintec and Tri-Lo-Sprintec both contain the same hormones, but Tri-Lo-Sprintec has a lower dose of estrogen. Tri-Sprintec has 35 mcg of ethinyl estradiol in each active pill, while Tri-Lo-Sprintec only has 25 mcg of ethinyl estradiol in the active pills. The amount of norgestimate found in each phase of pills is the same between these two medications. Your provider might suggest you take Tri-Lo-Sprintec if you need a lower dose of estrogen. While both [EDITOR|DRUG_DISPLAY_NAME]] and Tri-Lo-Sprintec are approved to prevent pregnancy, Tri-Sprintec can also be used to treat acne.
Yes, Tri-Sprintec is FDA-approved to treat moderate acne in certain people. If you're at least 15 years old and you're already planning on using a COC for birth control, then your provider might consider prescribing Tri-Sprintec to treat your acne.
It's important for you to take Tri-Sprintec every day for the medication to prevent pregnancy. But if you missed a dose, your next steps depend on when you missed it and how many pills you missed. If you only missed 1 pill, you can take the missed pill as soon as you remember and continue taking the next pill at your regular time. If you missed pills multiple days in a row, you might have to take 2 pills on the same day to make up for it. Or you might have to throw away your current pack and start a new pack. Since Tri-Sprintec is a triphasic birth control, it can be more complicated to make up for missed pills. Make sure to follow the instructions on the patient information sheet that was provided with your medication, or contact your provider or pharmacist. Also, ask them if you need to use another method of birth control to prevent pregnancy during this time.
Small amounts of Tri-Sprintec can pass into your breast milk and affect your baby. This medication can also lower the amount and quality of your breast milk, so it's not recommended to use until after you've stopped breastfeeding. It's best to speak to your provider to see which form of birth control is safe for you and your baby while you're breastfeeding.
Tri-Sprintec can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
If you smoke cigarettes, using combined oral contraceptives (COCs), like Tri-Sprintec, raises your risk for serious health problems, such as strokes, heart attacks, and blood clots. Females age 35 years and older who smoke are at even higher risk for these problems. If you smoke, talk with your provider about safer birth control alternatives.
Tri-Sprintec raises your risk of blood clots. These clots can occur anywhere in your body, including your lungs (pulmonary embolism or PE), legs (deep vein thrombosis or DVT), brain (stroke), and heart (heart attack). Get emergency help right away if you have any signs of a blood clot:
If you need to have surgery, tell your provider you're taking Tri-Sprintec. They might have you stop taking it 4 weeks before until 2 weeks after your surgery to lower your risk of blood clots. If you recently delivered a baby, you shouldn't start Tri-Sprintec until 4 weeks after delivery if you're not breastfeeding your child.
People who take Tri-Sprintec can sometimes experience irregular bleeding and spotting, especially during the first 3 months of taking this medication. Irregular bleeding can vary from slight staining to bleeding similar to a regular period. This problem might be temporary, so continue taking your medication as directed. Let your provider know if the bleeding is a problem for you and they can change your birth control. If you missed your period(s), contact your provider or get a pregnancy test to make sure you're not pregnant.
Tri-Sprintec can raise your blood pressure, so make sure you check your blood pressure while you're taking this medication. The risk is higher in females who are older and have been taking birth control for a long period of time. Females who have high blood pressure that's not under control shouldn't take Tri-Sprintec. Speak to your provider if this medication raises your blood pressure and they can help you pick a different method of birth control that's safer for you.
Tri-Sprintec can raise your levels of blood sugar and triglycerides (a type of fat). If you're prediabetic or diabetic, your risk of having your blood sugar rise is much higher. This is because Tri-Sprintec can prevent your body from breaking down sugar efficiently. Additionally, this medication can also affect your level of triglycerides. High triglycerides might lead to a higher risk of pancreatitis (pancreas inflammation). Speak with your provider before starting Tri-Sprintec if you have a history of high blood sugar or triglycerides. Your provider might help you choose another birth control or monitor your blood works more closely if you take this medication.
Study results are mixed, but there's a possibility that Tri-Sprintec and other COCs can raise your risk for breast and cervical cancer.
Don't take Tri-Sprintec if you currently have or have had breast cancer because some types of breast cancer grow faster in the presence of estrogen, a hormone in this medication. The risk of developing breast cancer might be slightly higher in females who currently take COCs, have taken them within the past 6 months, or are taking them for a long time (8 years or more). You can examine your breasts regularly at home or get yearly breast exams with your healthcare provider to help with early breast cancer detection. Let your provider know if you notice any new or abnormal lumps, pain, or swelling in your breasts.
Make sure you follow up with your provider to get proper screenings for cervical cancer. Report any signs of vaginal bleeding or discharge that's not normal.
Don't take Tri-Sprintec if you have liver problems, such as sudden liver infection caused by a virus, severe (decompensated) scarring of the liver, or liver tumors. Although rare, Tri-Sprintec can raise your risk of benign liver tumors. If you experience signs of liver problems, you should stop taking Tri-Sprintec and ask your provider for a different type of birth control. Signs of liver problems can include jaundice (yellowing of the skin or eyes), along with fever, tiredness, loss of appetite, or dark colored urine. People with liver problems might have trouble breaking down hormones.
Talk to your provider before starting Tri-Sprintec if you are taking Viekira Pak (dasabuvir / ombitasvir / paritaprevir / ritonavir) to treat hepatitis C. This medication can cause liver problems if you are taking it together with a COC. Stop taking Tri-Sprintec and discuss other birth control options with your provider if you need to start your treatment for hepatitis C. You can restart Tri-Sprintec 2 weeks after your Viekira Pak treatment is complete.
Let your provider know if you experience new or worsening migraines or headaches while taking Tri-Sprintec. You will have to stop your medication if your migraine or headache doesn't go away or becomes severe.
Let your provider know if you experience symptoms of depression or worsening depression while taking Tri-Sprintec. In cases of serious depression, your provider might have you stop taking it.
| Dosage | Quantity | Price as low as | Price per unit |
|---|---|---|---|
| 28 tablets | 3 packages | $22.14 | $7.38 |
Tri-Sprintec (and its branded generics) comes in a 28-day pack. Your medication might look different depending on which branded generic your provider prescribes. Please take the medication as instructed by your provider or following the directions on the package. In general:
The typical dose is 1 tablet by mouth at the same time every day for 28 days, following the order as instructed on the package.
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Tri-Sprintec will not be safe for you to take.