Oriahnn

• Risk factors: History of stroke | Personal or family history of blood clots | Women over 35 years of age who smoke | Obesity | Uncontrolled high blood pressure | Inactivity | History of vascular problems | History of heart rhythm problems | Over age 35 years of age with certain headaches | High cholesterol or fats in your blood

Estrogen and progestin combinations, like Oriahnn, raise your risk for stroke, heart attack, blood clots in the lungs (pulmonary embolism, or PE), and blood clots in the legs (deep vein thrombosis, or DVT). The risk is higher in women over 35 years of age who smoke, and women with uncontrolled high blood pressure, high cholesterol, vascular disease (e.g., coronary artery disease), or obesity. Get emergency help right away if you have any signs of a blood clot in the legs (cramps, swelling, pain, or muscle tightness) and lungs (trouble breathing, chest pain, or cough). If you have any signs of a stroke, such as weakness or numbness of the arms, legs, or face on one side of the body, slurred speech, blurred or loss of vision, headache, dizziness, loss of balance, trouble walking, or confusion, get emergency help right away. Also, tell all of your providers that you're taking this medication before you have a procedure or surgery. Your provider might have you stop taking Oriahnn 4 to 6 weeks before your procedure to lower your risk of clots.

• Risk factors: History of osteoporosis | Long-term use | Medications that might cause bone loss

Oriahnn might cause bone loss (a decrease in bone mineral density, or BMD). Sometimes the bone loss isn't completely reversible after stopping this medication. Your risk is higher if you're taking this medication for a long period of time, or if you're taking medications that might cause bone loss (e.g., oral corticosteroids, anti-seizure medications, proton pump inhibitors). If you have a history of osteoporosis, you shouldn't take this medication. Your provider will limit the amount of time you take Oriahnn to 24 months to lower your risk of bone loss. To help with this risk, ask your provider about taking calcium and vitamin D supplements during therapy.

• Risk factors: Personal or family history of breast cancer

There's a higher risk of developing breast cancer in women using estrogen alone or estrogen plus progestin, like Oriahnn. Lower your risk by working with your healthcare provider to take this medication for the shortest period of time. To help with early detection and to make sure there aren't any abnormal changes in your breasts, you can do monthly breast self-checks at home, yearly breast exams with your healthcare provider, and regular mammograms (breast x-rays). Contact your healthcare provider if you notice any abnormal changes or feel lumps, pain, or swelling in your breasts.

• Risk factors: History of depression or suicidal behaviors

Oriahnn can raise your risk of suicidal thoughts or behavior. Watch for new or worsening depression and suicidal thoughts or behavior, especially if you have a history of these. Let your healthcare provider know right away if you notice any unusual changes in your mood or behavior while taking this medication. If this happens, they might have you to stop taking Oriahnn.

Women with uncontrolled high blood pressure shouldn't take Oriahnn because it can make your blood pressure go even higher. Your provider might have you check your blood pressure regularly while taking this medication to make sure it doesn't get too high.

• Risk factors: History of gallbladder problems | History of liver problems

There's a higher risk of gallbladder problems in women using estrogen, an ingredient in Oriahnn. Your body also mainly breaks down or metabolizes Oriahnn in the liver. Your provider will consider this medication carefully if you have a history of liver problems (such as cholestatic jaundice) that have occurred with past estrogen use or during pregnancy.

Oriahnn can cause life-threatening liver damage. Your provider will monitor your labs to check for liver problems. Get medical help right away if you have nausea, vomiting, abdominal pain, loss of appetite, or yellowing of your skin or whites of your eyes because these can be signs of liver problems.

Oriahnn can make you bleed less, more, or longer than normal during your period. This change can make it harder to tell if you're pregnant or not, so your provider may have you take a pregnancy test before starting and while taking this medication. Be sure to watch for other signs of pregnancy like breast tenderness, weight gain, and nausea. If you suspect you're pregnant, stop taking Oriahnn and let your provider know.

• Risk factors: History of high triglycerides | Diabetes

Oriahnn can raise your blood sugar levels. If you have diabetes, you might need to check your blood sugar more often while taking this medication. Oriahnn can also raise triglyceride (fat) levels in your blood, which can lead to serious conditions like inflammation of your pancreas (pancreatitis). If you have a history of high triglycerides, try to make some dietary changes, like limiting salt and sugar, avoiding alcohol, and eating more fruits, vegetables, whole grains, lean meats, beans, and nuts. For more guidance on how to reduce your triglyceride levels, ask your healthcare provider. Your healthcare provider will monitor your triglyceride levels while you're taking this medication.

Oriahnn can cause hair loss and hair thinning. For some women, the hair loss can continue even after stopping the medication. Hair loss isn't dangerous, but it can be scary or bothersome. Talk to your provider if this concerns you.

• Risk factors: Low thyroid or cortisol hormone levels

Oriahnn can affect thyroid and cortisol hormone levels in your blood. If you take medications for low thyroid or cortisol hormone levels, you might need higher doses while taking Oriahnn. Your healthcare provider might have you take regular blood tests to check your hormone levels.

• Risk factors: Aspirin allergy

Although rare, some people are allergic to tartrazine (FD&C Yellow No. 5), an ingredient in Oriahnn capsules. Your risk might be higher if you have an aspirin allergy. Make sure to tell your provider about your past allergic reactions before you start taking this medication. Get medical help right away if you have trouble breathing after taking this medication.