The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Upper respiratory infections (29%)
- Infusion-related reactions (19%)
- Indigestion (8%)
- Shortness of breath (8%)
- Muscle spasms (8%)
- Joint pain (7%)
- Skin redness (7%)
- Bronchitis (7%)
- Vertigo or a spinning sensation (5%)
Less Common Side Effects
- Dry eye
- Blurry vision
- Eye floaters
Source: DailyMed
The following Onpattro side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- Infusion reactions—chest pain, shortness of breath or trouble breathing, feeling faint or lightheaded
- Low vitamin A level—change in vision, dry eyes, dry skin, frequent infections
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

