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Neulasta

Neulasta Side Effects

Kristianne Hannemann, PharmDCydnee Ng, PharmD
Reviewed by Kristianne Hannemann, PharmD, Cydnee Ng, PharmD
Last reviewed on July 8, 2022

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Bone pain (31%)
  • Pain in arms and legs (9%)

Less Common Side Effects

  • Injection site reaction

Neulasta serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Shortness of breath or trouble breathing
  • Ruptured spleen: pain in your left upper stomach or shoulder
  • Serious allergic reaction: rash, trouble breathing, swelling of your tongue, lips, or throat

Source: FDA

The following Neulasta side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Chills

cough

fever

sore throat

ulcers, sores, or white spots in the mouth

Rare

Bluish lips or skin

pain, left upper abdomen or shoulder

tightness in the chest

trouble breathing

Incidence not known

Black, tarry stools

bleeding gums

bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site

blisters in the skin

blood in the urine or stools

chest pain

cloudy urine

decrease in how much or how often you urinate

difficulty with swallowing

dizziness

fainting or lightheadedness

fast heartbeat

flushing or redness of the skin

hives or welts, skin rash

itching, puffiness, or swelling of the eyelids or around the eyes, face, lips, or tongue

large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs

lower back or side pain

nausea

painful or difficult urination

pinpoint red spots on the skin

sores on the skin

stomach pain

swelling of the hands, ankles, feet, or lower legs

swollen glands

unusual bleeding or bruising

unusual tiredness or weakness

unusually warm skin

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Bone pain

chest pain

difficult or labored breathing

eye pain

general feeling of illness

headache

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Belching

change in sense of taste

constipation

cracked lips

diarrhea

hair loss or thinning of the hair

heartburn

indigestion

joint pain

lack or loss of strength

loss of appetite

muscle soreness

swelling or inflammation of the mouth

trouble sleeping

vomiting

weakness, generalized

weight loss

Incidence not known

Body produces substance that can bind to drug making it less effective or cause side effects

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Why trust our experts?

Kristianne Hannemann, PharmD, is a licensed pharmacist in California. She has been a retail pharmacy manager and staff pharmacist for over 7 years and has contributed drug information content to different health companies.
Cydnee Ng, PharmD
Reviewed by:
Cydnee Ng, PharmD
Cydnee Ng, PharmD, is a drug information pharmacist at GoodRx, where she lends her expertise to providing reader-friendly, accessible content about medications. She holds her pharmacist license in California.

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