Skip to main content
Methscopolamine Coupon - Methscopolamine 2.5mg tablet

methscopolamine

Generic Pamine
Used for Peptic Ulcer
Used for Peptic Ulcer

Methscopolamine is an anticholinergic medication that's used to treat peptic ulcers in adults. Although its brand name Pamine is no longer available, the generic methscopolamine tablets can be prescribed. This medication is taken by mouth before meals and at bedtime. Side effects can include dry mouth, blurry vision, and sleepiness.

Reviewed by:
reviewer
Robert Chad Hakim, PharmD, BCCCP
reviewer
Cydnee Ng, PharmD
Last reviewed on August 18, 2021
BasicsSide effectsPros & consPharmacist tipsFAQsWarningsDosageInteractionsCostContraindicationsAlternativesImagesReferencesPricesMedicare
basics-icon

What is Methscopolamine?

What is Methscopolamine used for?

How Methscopolamine works

Methscopolamine is an anticholinergic medication. It works by blocking a chemical called acetylcholine from attaching to its receptors in your stomach and intestines. This helps lower the amount of acid in the stomach and slow movement in the gut. These actions help with pain and discomfort from stomach ulcers (peptic ulcers).

Are you looking for information on scopolamine (Transderm Scop) instead?

Drug Facts

Common BrandsPamine (brand name no longer available)
Drug ClassAnticholinergic
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only
coupon-save-icon

Get your GoodRx coupon

Avg retail price
$153.18(save 75.00%)
GoodRx discount
$38.29
See prices
basics-icon

What are the side effects of Methscopolamine?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

Other Side Effects

  • Headache
  • Nervousness
  • Confusion
  • Sleepiness
  • Dizziness
  • Weakness
  • Blurry vision
  • Loss of taste
  • Difficulty urinating
  • Bloating
  • Less sweating
  • Difficulty sleeping
  • Fast heart rate

Source: DailyMed

The following side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Rare

Confusion (especially in the elderly)

dizziness, lightheadedness that continues, or fainting

eye pain

skin rash or hives

Incidence not known

Cough

difficulty with swallowing

fast irregular, pounding, or racing heartbeat or pulse

fever

hives or welts

hoarseness

irritation

itching skin

joint pain, stiffness, or swelling

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

redness of the skin

shortness of breath

skin rash

tightness in the chest

trouble with breathing

wheezing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Constipation

decreased sweating

dryness of the mouth, nose, throat, or skin

Less common or rare

Bloated feeling

blurred vision

difficult urination

difficulty with swallowing

drowsiness

false sense of well-being

headache

increased sensitivity of eyes to light

loss of memory

nausea or vomiting

redness or other signs of irritation at the place of injection

trouble with sleeping

unusual tiredness or weakness

Incidence not known

Decreased interest in sexual intercourse

inability to have or keep an erection

loss in sexual ability, desire, drive, or performance

loss of taste

For patients using scopolamine:

After you stop using scopolamine, your body may need time to adjust. The length of time this takes depends on the amount of scopolamine you were using and how long you used it. During this period of time check with your doctor if you notice any of the following side effects:

Anxiety

irritability

nightmares

pupil of one eye is larger (patch only)

sensitivity of eyes to light (patch only)

trouble in sleeping

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

pros-and-cons

Pros and cons of Methscopolamine

thumbs-up

Pros

Helps with pain and cramping due to stomach ulcers

Available as tablets taken by mouth

thumbs-down

Cons

Not a common choice because it doesn't heal or prevent stomach ulcers

Taken 4 times a day

pharmacist-tips

Pharmacist tips for Methscopolamine

pharmacist

  • Take methscopolamine on an empty stomach 30 minutes before each meal and at bedtime.

    • Methscopolamine can cause sleepiness, dizziness, and blurry vision. These side effects can affect your ability to think, focus, and react. Don't drive, operate machinery, or do anything that requires concentration until you know how this medication affects you.

      • Dry mouth is a possible side effect of methscopolamine because the medication can cause your body to make less saliva. Make sure to drink plenty of water while you're taking this medication to help relieve dry mouth.

        • It's also important to stay hydrated while you're taking methscopolamine because the medication can make it easier for you to overheat in hot temperatures. Methscopolamine can cause your body to make less sweat, which can affect how well your body can cool down.

          • Avoid alcohol while you're taking methscopolamine. It can make methscopolamine side effects like sleepiness worse, putting you at risk for falls or other accidents.

            • Don't take methscopolamine with other anticholinergics, like diphenhydramine (Benadryl) or glycopyrrolate (Robinul). These medications work similarly to methscopolamine, and they have similar side effects. Taking anticholinergic medications with methscopolamine can make side effects, like dry mouth, headache, and dizziness, worse. It can also lead to more serious side effects, like overheating, confusion, and agitation.

              • Talk to your care team if you want to take antacids for your stomach symptoms along with methscopolamine. Taking antacids at the same time as this medication can lower the amount of methscopolamine that's absorbed into the body, which can make it not work as well. Your care team can help you come up with a schedule to get the best results from both types of medications.

                faqs

                Frequently asked questions about Methscopolamine

                Is methscopolamine over the counter?
                No, methscopolamine isn't available over the counter. You'll need a prescription for it from a healthcare professional.
                Can you take methscopolamine for IBS?
                Methscopolamine isn't approved for treating irritable bowel syndrome (IBS) or relieving symptoms of IBS. But there are other anticholinergics that are specifically approved for IBS, such as dicyclomine (Bentyl) and hyoscyamine. Speak with your gastroenterologist about options for treating IBS that might be right for you.
                Can you take methscopolamine for diarrhea?
                Methscopolamine isn't FDA approved to treat diarrhea. Also keep in mind that diarrhea can sometimes be an early sign of a blockage in the gut and taking methscopolamine in these situations can be harmful. Talk to a member of your care team if you're having diarrhea. They can speak with you about appropriate treatment options.
                What's the difference between methscopolamine and scopolamine?
                Although their names sound similar, methscopolamine and scopolamine are completely different medications. Methscopolamine is a tablet that you take by mouth to treat peptic ulcers. On the other hand, scopolamine (Transderm Scop) is a patch that's applied to the skin for preventing nausea and vomiting from motion sickness. Don't use these two medications together since they're both anticholinergic medications. Taking more than one anticholinergic medication at the same time can lead to serious side effects, like confusion, disorientation, and agitation.
                Can children take methscopolamine?
                No. Methscopolamine hasn't been studied in children, so it's not known how safe the medication is or how well it works in children. Some possible options for treating peptic ulcers in children include medications that lessen stomach acid. Speak with a healthcare professional to see what treatment option is best for your child.
                Can you take methscopolamine during pregnancy?
                Talk to your gastroenterologist about the risks and benefits of taking methscopolamine if you're pregnant or thinking of becoming pregnant. It's not completely clear how safe the medication is if it's taken during pregnancy.
                Can you breastfeeding while you're taking methscopolamine?
                Don't take methscopolamine if you're breastfeeding unless your prescriber specifically said it's safe for you. This medication can lessen the amount of breast milk you make. Speak with your prescriber or obstetrician-gynecologist (OB-GYN) for more information about feeding options.
                GoodRxEducationalIcon

                How to save using GoodRx

                Compare Prices
                1. Compare PricesSpecify your dosage and quantity to find out exactly how much you can save.
                Select your free coupon
                2. Select your free couponYou can use the displayed coupon, or compare prices at other pharmacies near you.
                Show coupon to your pharmacist
                3. Show coupon to your pharmacistPresent your printed or electronic coupon when you pick up your prescription.
                Get free couponLearn more
                warings-icon

                What are the risks and warnings for Methscopolamine?

                Methscopolamine can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

                risk-warning

                Changes to certain bodily functions

                • Risk factors: Age 65 years or older

                  Methscopolamine can cause changes to your autonomic nervous system, which controls the functions of your body that you don't have to think about. For example, methscopolamine can cause the muscles of your gut to slow down, which can lead to constipation. This medication can also make you have less saliva in the mouth, leading to dry mouth. Methscopolamine can also affect other functions, such as your heartbeat or vision. Let your healthcare team know if you experience any unusual and bothersome changes to your bodily functions while you're taking this medication.

                  risk-warning

                  Risk for heat exhaustion or heatstroke

                  • Risk factors: Hot weather | In a warm environment

                    Methscopolamine can make you sweat less, which affects how well your body can cool itself down. This can put you at risk for fever, heat exhaustion, and heatstroke, especially when you're in a very warm environment. Don't take methscopolamine without asking your HCP first if you have a fever because the medication might make it worse.

                    Some early symptoms of heat exhaustion or heatstroke can include feeling thirstier, urinating less, having dry mouth, or feeling tired. But get medical help as soon as possible if these symptoms become severe or if you have additional symptoms like muscle cramping; faster or weaker pulse; confusion; hot, dry, red skin; or a very high fever.

                    risk-warning

                    Not appropriate for people with an intestinal (gut) blockage

                    • Risk factors: Ileostomy or colostomy | Ulcerative colitis | Taking high doses of methscopolamine

                      Let your prescriber know if you have any diarrhea. Sometimes, diarrhea is an early sign that you have a blockage in your gut, especially if you've had an ileostomy or colostomy (or any similar procedures) done. Taking methscopolamine in these situations can be harmful.

                      In addition, don't take methscopolamine if you have severe ulcerative colitis. Taking large doses of methscopolamine can slow the gut down to a stop. This can lead to serious problems, like severe inflammation and swelling of the colon.

                      risk-warning

                      Muscle weakness

                      • Risk factors: Taking too much methscopolamine

                        Make sure to take methscopolamine exactly as prescribed. Don't change your dose without talking to your prescriber. Taking too much methscopolamine can cause muscle weakness and paralysis. Stop taking methscopolamine and contact your prescriber right away if you notice muscle weakness or numbness in your body.

                        dosage

                        Methscopolamine dosage forms

                        The average cost for 60 tablets of 2.5mg of Methscopolamine is $38.29 with a free GoodRx coupon. This is 75% off the average retail price of $153.18.
                        tablet
                        Tablet
                        DosageQuantityPrice as low asPrice per unit
                        2.5mg60 tablets$38.29$0.64
                        5mg180 tablets$114.57$0.64

                        Typical dosing for Methscopolamine

                        The typical dose is 2.5 mg or 5 mg by mouth 30 minutes before meals, and 2.5 mg or 5 mg at bedtime.

                        interactions

                        Interactions between Methscopolamine and other drugs

                        Methscopolamine may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Methscopolamine. Please note that only the generic name of each medication is listed below.

                        Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking any of these medicines, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

                        Using medicines in this class with any of the following medicines is not recommended. Your doctor may decide not to treat you with a medication in this class or change some of the other medicines you take.

                        Using medicines in this class with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                        drug-cost

                        How much does Methscopolamine cost?

                        To access savings, use a GoodRx coupon and pay just a fraction of the retail price.
                        Methscopolamine (generic)
                        GoodRx lowest price

                        $38.29

                        (save 75.00%)
                        View prices & coupons
                        contraindications-icon

                        Methscopolamine contraindications

                        Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Methscopolamine will not be safe for you to take.
                        alternatives

                        What are alternatives to Methscopolamine?

                        There are a number of medications that your doctor can prescribe in place of Methscopolamine. Compare a few possible alternatives below.
                        Methscopolamine
                        Used for:
                        $38.29 Lowest GoodRx priceView Prices
                        Omeprazole (Prilosec)
                        Used for:

                        • Gastroesophageal reflux disease (GERD)

                        • Inflamed esophagus due to GERD

                        $5.88 Lowest GoodRx priceView Prices
                        Lansoprazole (Prevacid)
                        Used for:
                        $10.80 Lowest GoodRx priceView Prices
                        images

                        Methscopolamine images

                        White Round B And 191 - Methscopolamine Bromide 2.5mg Tablet
                        This medicine is White, Round Tablet Imprinted With "191" And "B".White Round B And 191 - Methscopolamine Bromide 2.5mg Tablet
                        White Round S15 - Methscopolamine Bromide 2.5mg Tablet
                        This medicine is White, Round Tablet Imprinted With "S15".White Round S15 - Methscopolamine Bromide 2.5mg Tablet

                        Get savings updates for Methscopolamine

                        Receive price alerts, news, and other messages from GoodRx about Methscopolamine and other healthcare topics and relevant savings offers.

                        By providing your email, you consent to receive marketing communications from GoodRx, which may include content and/or data related to men’s health, women's health, reproductive care, or sexual health. You agree to the GoodRx Terms of Use and acknowledge the Privacy Policy. You can unsubscribe at any time.

                        References

                        Best studies we found

                        Aarkish Pharmaceuticals NJ Inc. (2024). Methscopolamine bromide- methscopolamine bromide tablet [package insert]. DailyMed.

                        Belkind-Gerson, J. (2023). Peptic ulcer in children. Merck Manual Consumer Version.

                        Drugs and Lactation Database (LactMed®). (2024). Methscopolamine bromide. National Institute of Child Health and Human Development.

                        View All References (4)

                        MedlinePlus. (2022). Ileostomy.

                        MedlinePlus. (2024). Agitation.

                        MedlinePlus. (2024). Colostomy.

                        Schafer, T. W., et al. (2021). Peptic ulcer disease overview. American College of Gastroenterology.

                        GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
                        Was this page helpful?

                        Browse medications

                        View All

                        Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.