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Meropenem

Meropenem Side Effects

Aileen Chu, PharmD, BCPSAllison Gourley, PharmD
Reviewed by Aileen Chu, PharmD, BCPS, Allison Gourley, PharmD
Last reviewed on October 2, 2023

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Headache (up to 8%)
  • Nausea (up to 8%)
  • Constipation (up to 7%)
  • Diarrhea (up to 7%)
  • Anemia (low red blood cell count; up to 6%)
  • Pain (up to 5%)
  • Vomiting (up to 4%)

Less Common Side Effects

  • Inflammation around the area where the medication is injected
  • Itching
  • Rash
  • Trouble breathing
  • Sepsis (bloodstream infection)

Meropenem serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Allergic reactions: itching; hives; trouble breathing; trouble swallowing; swelling of your hands, face, or mouth
  • Severe skin reactions: skin pain, red rash or red blotches on your skin, blisters and sores on the skin, peeling skin
  • Severe diarrhea: watery or bloody stools, painful stomach cramps, signs of dehydration (e.g., dry mouth, headaches, urinating less often than normal)
  • Seizures
When do Meropenem possible side effects begin and end?
Time passed since treatment started:
H
D
W
M
Risk of diarrhea

Source: DailyMed

The following Meropenem side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

Less common

Bluish lips or skin

chills

cold, clammy skin

confusion

dizziness

fainting

fast heartbeat

fast, weak pulse

fever

itching, skin rash

lightheadedness

rapid, shallow breathing

sweating

Rare

Agitation

black, bloody, or tarry stools

black, bloody vomit

bloating or swelling of the face, arms, hands, lower legs, or feet

blurred vision

burning sensation while urinating

burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

cough

dark urine

decreased awareness or responsiveness

decreased urine output

depression

diarrhea (watery and severe), which may also be bloody

difficult or painful urination

difficulty with breathing

dilated neck veins

extreme tiredness or weakness

fever with or without chills

headache

hives or welts

hostility

irregular breathing

irritability

light-colored stools

loss of consciousness

muscle twitching

nausea

no blood pressure or pulse

nosebleed

pale skin

pounding in the ears

rapid weight gain

seizures

severe constipation

severe vomiting

severe sleepiness

slow, irregular heartbeat

stomach cramps, severe

tightness in the chest

troubled breathing with exertion

unconsciousness

unpleasant breath odor

unusual bleeding or bruising

unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness

unusual weight gain or loss

vomiting of blood or material that looks like coffee grounds

weight gain

white patches in the mouth, tongue, or throat

yellow eyes or skin

Incidence not known

Back, leg, or stomach pains

bleeding gums

blistering, peeling, or loosening of the skin

chest pain

confusion as to time, place, or person

cough

general body swelling

general feeling of tiredness or weakness

hoarseness

holding false beliefs that cannot be changed by fact

joint or muscle pain

large, hive-like swelling on the face, eyelids, tongue, throat, hands, legs, feet, or genitals

loss of appetite

lower back or side pain

red skin lesions, often with a purple center

red, irritated eyes

seeing, hearing, or feeling things that are not there

sore throat

sores, ulcers, or white spots in the mouth or on the lips

swollen glands

unusual excitement, nervousness, or restlessness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Constipation

redness and swelling at the injection site

Less common

Body aches or pain

cold hands and feet

cold sweats

congestion

cool pale skin

dryness or soreness of the throat

increased hunger

indigestion

nightmares

passing of gas

redness, swelling, or soreness of the tongue

runny nose

shakiness

slurred speech

sneezing

stomach pain, fullness, or discomfort

trouble swallowing

vaginal yeast infection

voice changes

Rare

Belching

excess air or gas in the stomach or bowels

full feeling

heartburn

redness of the skin

sleepiness or unusual drowsiness

trouble sleeping

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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