Skip to main content
Lotrel

Lotrel Side Effects

Robert Chad Hakim, PharmD, BCCCPConnie Zheng, PharmD
Reviewed by Robert Chad Hakim, PharmD, BCCCP, Connie Zheng, PharmD
Last reviewed on March 7, 2023

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Cough (3%)
  • Headache (2%)
  • Swelling in the hands and feet (2%)
  • Dizziness (1%)

Less Common Side Effects

  • Rash
  • Reddening of skin (flushing)
  • Sleepiness

Lotrel serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Angioedema (severe swelling): swelling of the face, arms or legs, lips, tongue, or throat
  • Heart attack: tightness and pain in the chest, neck, arms, or back; cold and clammy skin; sweating; dizziness; tiredness
  • Serious kidney problems: urinating less often than usual, swelling in your feet, ankles, or hands, unexplained weight gain
  • High blood potassium levels: nausea, muscle weakness, tingling sensation, abnormal heartbeat
  • Dangerously low blood pressure: dizziness, lightheadedness, pale skin, feeling faint or fainting
  • Severe liver problems: swelling of your stomach, yellowing of your skin or the whites of your eyes, confusion, dark or brown urine
When do Lotrel possible side effects begin and end?
Time passed since treatment started:
H
D
W
M
Dizziness
Cough
Swelling in the hands and feet
If a line continues to the right, you'll likely keep experiencing this side effect once it starts.

Source: DailyMed

The following Lotrel side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

Confusion

dizziness, lightheadedness, or fainting

fast or irregular heartbeat

nervousness

numbness or tingling in the hands, feet, or lips

swelling of the ankles, feet, or lower legs

weakness or heaviness of the legs

Rare

Bleeding gums

chills

fever

nausea or vomiting

nosebleeds

pale skin

sores, ulcers, or white spots on the lips, tongue, or inside the mouth

stomach pain or bloating with fever, nausea, or vomiting

swelling of the face, mouth, hands, or feet

trouble with swallowing or breathing (sudden) or hoarseness

unusual bleeding or bruising

unusual tiredness or weakness

yellow eyes or skin

Incidence not known

Chest pain

heartburn

pain or burning in the throat

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Cough (dry and continuous)

feeling of warmth

redness of the face, neck, arms, and occasionally upper chest

sleepiness

Incidence not known

Belching

blistering, crusting, irritation, itching, or reddening of the skin

body aches or pain

cracked, dry, or scaly skin

decreased interest in sexual intercourse

difficulty having a bowel movement

frequent urination

inability to have or keep an erection

increased volume of pale, dilute urine

indigestion

lack or loss of strength

loss in sexual ability, desire, drive, or performance

muscle or bone pain

shakiness in the legs, arms, hands, or feet

stomach discomfort or upset

sudden sweating

swelling

tender, swollen glands in the neck

trembling or shaking of the hands or feet

trouble with sleeping

voice changes

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

GoodRx icon

Other Lotrel articles

GoodRx icon

Other ACE Inhibitor / Calcium Channel Blocker Combinations side effects articles

Was this page helpful?