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Loperamide

Loperamide Side Effects

Kristianne Hannemann, PharmDAllison Gourley, PharmD
Reviewed by Kristianne Hannemann, PharmD, Allison Gourley, PharmD
Last reviewed on May 7, 2024

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Dizziness
  • Drowsiness
  • Tiredness
  • Constipation

Less Common Side Effects

  • Nausea
  • Stomach cramps

Loperamide serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Stomach swelling (bloating)
  • Severe allergic reaction: hives; trouble breathing; swelling of the lips, face, throat, or tongue

Source: DailyMed

The following Loperamide side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Rare

Bloating

constipation

loss of appetite

nausea

stomach pain

vomiting

Incidence not known

Blistering, peeling, loosening of skin

chest pain or discomfort

chills

cough

decrease in urine volume

decrease in frequency of urination

difficulty in passing urine

diarrhea

fainting

fast, pounding, or irregular heartbeat or pulse

hives or welts, itching, rash

irregular or slow heartbeat

joint or muscle pain

large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, sex organs

no blood pressure or pulse

painful urination

palpitations

red irritated eyes

redness of the skin

red skin lesions, often with a purple center

sores, ulcers, or white spots in the mouth or on the lips

sore throat

stopping of heart

unconsciousness

unusual tiredness or weakness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Rare

Acid or sour stomach

belching

dizziness

drowsiness

dryness of mouth

excess air or gas in the stomach or bowels

full feeling

heartburn

indigestion

passing gas

stomach upset

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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