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Lidoderm

Lidoderm Side Effects

Ally Tsai, PharmDDaisy Chau, PharmD
Reviewed by Ally Tsai, PharmD, Daisy Chau, PharmD
Last reviewed on April 23, 2025

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Blisters
  • Bruising
  • Burning sensation
  • Changes in skin color
  • Rash or redness
  • Swelling
  • Peeling or flaking skin
  • Itching
  • Small bumps or spots
  • Tiny red or purple dots under the skin
  • Tingling or numbness in the area

Less Common Side Effects

  • Confusion
  • Dizziness
  • Headache
  • Feeling faint
  • Weakness or low energy
  • Tingling or numbness in the skin
  • Nausea
  • Vomiting
  • Changes in taste
  • Blurred vision
  • Ringing in the ears
  • Tremors

Lidoderm serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Blood problems (methemoglobinemia): pale, gray, or blue-colored skin, headache, fast heartbeat, shortness of breath, lightheadedness, tiredness, seizures, coma
  • Too much lidocaine: numbness around the mouth, tingling in the tongue, dizziness, ringing in the ears, blurred vision
  • Serious allergic reactions: Swelling of the face, difficulty breathing, trouble speaking, throat tightening up, red and itchy rash, lightheadedness, clammy skin
When do Lidoderm possible side effects begin and end?
Time passed since treatment started:
M
H
D
W
M
Bruising
Mild burning sensation
Itching
Small bumps or blisters

Source: DailyMed

The following Lidoderm side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

Blurred vision or other changes in vision

burning feeling at site of application

redness of the white part of eyes or inside of eyelids

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Headache

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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