Typical dosage for Kyprolis
The dose is based on your body surface area (BSA, m2 units), which is calculated using your height and weight measurements. If your BSA is above 2.2 m2, your dose will be calculated using a BSA of 2.2 m2.
Kyprolis is given as an infusion through the veins (IV), usually once or twice a week. In general, the medication is given between weeks 1 and 3 in every 4-week treatment cycle.
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For once-weekly dosing: The usual starting dose is 20 mg/m2 given IV once a week. After the first week, your provider might raise your dose to 70 mg/m2 once a week.
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For twice-weekly dosing: The usual starting dose is 20 mg/m2 given IV twice a week. After the first week, your provider might raise your dose to either 27 mg/m2 or 56 mg/m2 twice a week.
Your dose and your treatment schedule will vary depending on whether you’re taking Kyprolis by itself or together with other medications for your cancer. Your dose might also differ if you have liver problems or have serious side effects from Kyprolis.
