The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Diarrhea (70%)
- Nausea (69%)
- Lower blood cell counts (up to 64%)
- Fatigue (59%)
- Vomiting (56%)
- Signs of stress to the liver or kidney on blood tests (up to 52%)
- Muscle or bone pain (41%)
- Liver injury (37%)
- Kidney injury (36%)
- Shortness of breath (35%)
- Swelling (32%)
- Loss of appetite (30%)
Note: Side effects noted above were reported in studies where [[EDITOR|DRUG_DISPLAY_NAME]] was used alone for lung cancer.
Less Common Side Effects
- Cough
- Lung infection
- Dizziness
- Constipation
- Stomach pain
- Abnormal heart rhythm
Krazati serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Severe digestive system problems: stomach pain, black or bloody bloody stools, severe constipation
- Life-threatening abnormal heart rhythm: chest pain, shortness of breath, dizziness, fluttering or pounding heart beat
- Liver injury: pain in the right side of the stomach, yellowing of the eyes or skin, dark or brown urine
- Lung damage: cough, shortness of breath, fever
Source: DailyMed
The following Krazati side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- Bowel blockage—stomach cramping, unable to have a bowel movement or pass gas, loss of appetite, vomiting
- Dry cough, shortness of breath or trouble breathing
- Heart rhythm changes—fast or irregular heartbeat, dizziness, feeling faint or lightheaded, chest pain, trouble breathing
- Kidney injury—decrease in the amount of urine, swelling of the ankles, hands, or feet
- Liver injury—right upper belly pain, loss of appetite, nausea, light-colored stool, dark yellow or brown urine, yellowing skin or eyes, unusual weakness or fatigue
- Stomach bleeding—bloody or black, tar-like stools, vomiting blood or brown material that looks like coffee grounds
- Sudden or severe stomach pain, bloody diarrhea, fever, nausea, vomiting
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
- Diarrhea
- Fatigue
- Loss of appetite
- Muscle pain
- Nausea
- Vomiting
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