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THC Dosage: What’s the Right (and Safe) Amount?

Alex Eastman, PhD, RNKaren Hovav, MD, FAAP
Written by Alex Eastman, PhD, RN | Reviewed by Karen Hovav, MD, FAAP
Updated on August 22, 2025

Key takeaways:

  • There are no established guidelines on how much THC (tetrahydrocannabinol) is safe to consume. But if you’re prescribed a medication like dronabinol (Marinol) or nabilone (Cesamet), you’ll get information about your dosage.

  • The standard unit of measurement for research on THC is 5 mg. This helps researchers study the effects and uses of THC, but it isn’t a recommendation on how much to take.

  • Scientists continue to learn more about how much THC is safe to consume, including dosages for edibles and other formulations.

  • THC affects people differently, and the timeline of effects depends on the type of product you’re using. So it’s best to start slowly and with a low dose under 2.5 mg.

Cannabis products with THC (tetrahydrocannabinol) have grown in popularity as more U.S. states legalize their use. And with all of the different products out there, many people are left wondering whether there’s a “right” or safe amount of THC to consume. Many THC edibles come in units of 5 mg and 10 mg. But how can you know how much THC is right for you?

The reality is that figuring out THC dosage can be quite tricky, since THC affects people in different ways. Let’s take a closer look at the risks and benefits of THC and how to understand dosages for edibles and other products with THC.

What’s the recommended standard dosage of THC?

There’s no “standard dosage” of THC. And THC is one among many active chemicals (cannabinoids) in cannabis plants. THC is well known for its psychoactive effects, or the feeling of a “high” it can create.

Researchers have pushed to establish a “standard unit of measurement” to better understand the possible uses of THC and how it affects people. The National Institute on Drug Abuse (NIDA) defined a standard unit of THC as any cannabis formulation that has 5 mg of THC

This standard of measurement helps scientists interpret and compare findings from different studies. And this can help them better understand the effects of THC on certain high-risk groups, like pregnant women and teens. But this standard measurement doesn’t mean that it’s safe or recommended to take that amount of THC. 

Cannabis manufacturers and some organizations offer their own recommendations for how much THC to take. But these recommendations depend on why someone is using cannabis in the first place. 

For example, for chronic pain, a group of experts recommend starting with high-concentration CBD (cannabidiol) and then adding THC as needed to help with symptoms. The experts recommend starting at 2.5 mg of THC and titrating (slowly increasing) to no more than 40 mg of THC per day.

What’s a safe amount of THC to consume?

There are no official recommendations on what’s a safe amount of THC to take. So it’s best to check in with your primary care provider before considering THC. And, in terms of legal safety, keep in mind that cannabis is still illegal on the federal level. So make sure to check your state’s cannabis laws first.

Researchers continue to study what a safe amount of THC looks like in practice. This is tough, because everyone responds to cannabis differently. And more research is needed to better understand both the short- and long-term effects of cannabis. Decades of research strongly suggests that cannabis isn’t good for the developing teen brain

GoodRx icon
  • Using responsibly: These cannabis safety tips can help you make informed decisions about how much THC or CBD to use. 

  • Get “unhigh” fast: It’s hard to predict how cannabis will make you feel, especially if you’ve never tried it. If you’re high and don’t want to be, try our expert tips on how to sober up safely.

  • Avoid the high: Don’t want the mind-altering effects of cannabis? Follow these suggested guidelines for minimizing the high associated with THC.

The way cannabis affects you can depend on: 

  • The particular type of product

  • How much you use

  • How you take it

  • Your level of tolerance

This is why experts recommend starting slowly and with low doses. For edibles, this can look like 2.5 mg or less of THC. But it’ll likely take some trial and error to figure out what feels like a safe and helpful amount for you.

Keep in mind: The quality and safety of cannabis products isn’t always clear. Regulations vary by state, and so the labeling of THC products can vary. Be sure to shop at regulated dispensaries and check labels carefully.

Does the THC dosage vary in different marijuana products?

There are different ways to consume cannabis products. And so THC dosage varies too. Also, the exact contents of cannabis products varies. That means not all of them have THC. Some have only CBD, while others combine both. And the mix of ingredients, or formulations, can change how the product affects you. For example, CBD might lessen the intoxicating effect of THC. And the amount of THC varies by product type. 

Let’s take a look at different products that contain THC and the effects they can have.

Medications with THC

The FDA has approved two medications that contain synthetic (lab-made) THC. These medications can help treat nausea and vomiting from chemotherapy and increase appetite for people living with HIV:

  • Dronabinol (Marinol) is available in 2.5 mg, 5 mg, and 10 mg capsules. To treat nausea and vomiting, your dose will likely be based on your height and weight. This may be 5 mg taken 1 to 3 hours before chemotherapy and then every 2 to 4 hours after treatment. To stimulate appetite, a typical starting dose is 2.5 mg twice daily, about 1 hour before you eat.

  • Nabilone (Cesamet) is available in 1 mg capsules. The recommended dosage for this medication is 1 mg or 2 mg twice per day. 

If you’re taking prescription THC medications like Marinol or Cesamet, your healthcare team will talk to you about the recommended dosage for you. It’s important to take these medications as prescribed and to not take more than the recommendations.

Smokable cannabis

The amount of THC in cannabis you smoke or vaporize can vary a lot. Some hemp-derived pre-rolled cigarettes (joints) have as little as 0.1% THC. But dispensary pre-rolls can have 20% to 30% THC by weight. 

When you inhale THC, the effects occur within minutes — before wearing off in about 2 to 3 hours. The effects are quick because the active ingredients are absorbed through the lungs directly into the bloodstream, then to the brain.

Weed edibles and THC-infused beverages

Edibles are foods and drinks that have cannabis infused or cooked into them. There’s a wide range of edible products, including baked goods, candies, and mints. 

The amount of THC in edibles and beverages can also vary a lot. Some states offer low-dose edibles, with as little as 1 mg per serving. And other products follow the standard measurement of 5 mg.

Keep in mind that when you eat or drink THC, you may not feel the effects for up to 2 hours. It can take up to 4 hours before you feel the full effect. And effects can last up to 12 hours. This timeline is longer because edibles must move through your digestive tract and then your liver before getting to your bloodstream and finally your brain.

Concentrates

Cannabis concentrates are made by stripping the plant of its resin using carbon dioxide, alcohol, butane, and other methods. These methods create very high concentrations of THC that can range from 54% to 80%. 

Concentrates include oils and wax, which are then vaped or inhaled. Their effects can be quick and powerful. Keep in mind that larger amounts of THC are more likely to lead to side effects like anxiety, agitation, and paranoia.

Are some marijuana products stronger than others, regardless of the THC amount?

Researchers are still learning about how different cannabis products and THC levels affect people. Some research suggests that smoking or vaping cannabis may affect people differently than consuming edibles. A big part of this comes down to bioavailability, or how much of the substance your body can actually process and use. In general, the bioavailability of inhaling (smoking) THC is higher than eating or drinking it.

And remember that smoking or vaping causes a faster response, since the drug reaches the brain within minutes. But when you eat an edible, it can take 30 to 120 minutes to feel the effects, which also last for 6 to 12 hours. So, it’s a good idea to wait 2 to 3 hours to see how you feel before consuming more.

Can you overdose on THC, and what happens if you take too much?

An overdose is when you take too much of a medication or substance, and this is possible with cannabis. But an overdose from cannabis is rarely deadly. 

THC side effects are more likely with high doses, but they can happen at any dose. These side effects include:

  • Anxiety

  • Panic

  • Paranoia

  • High blood pressure (along with increased risk of heart attack and stroke)

  • Increased heart rate

  • Nausea and vomiting

  • Psychotic symptoms, like hallucinations and delusions

Edibles may be more likely to trigger an overdose. Since it takes longer to feel their effect, people might take a second dose without realizing that their body is still processing their first dose. 

Although taking too much THC may feel very uncomfortable, do your best to stay calm. There’s no way to sober up quickly, but self-care can go a long way while you wait it out. Be sure to get medical help if you or someone you know can’t stop vomiting or develops aggression, confusion, or extreme anxiety from an overdose.

What are the benefits of taking THC?

Medical cannabis has been used to treat different health conditions. Research on the possible benefits of cannabis is limited and ongoing. But it does show promise to help with:

Since research suggests that cannabis can help people manage long-term (chronic) pain, scientists are also exploring it as a possibly safer alternative to opioids

Is it safe to use larger doses of THC?

Larger doses of THC pose greater risks. Consuming higher amounts of THC can increase your risk of addiction and dependence. It can also increase your chances of needing emergency care and experiencing psychosis-like symptoms, such as hallucinations and delusions. Overall, it’s safest to avoid large doses of THC and stick to the dosage recommended by your healthcare team.

How has the THC content in marijuana changed over the years?

The potency (strength) of cannabis has increased over the past 25 years. In 1995, the average amount of THC in cannabis was about 4%. By 2022, it rose to over 16%. 

During this time, the number of cannabis-related emergency room visits has also risen. While more research is needed, increased potency may explain some cases requiring hospitalizations.

Frequently asked questions

How long THC stays in your body depends on how much and how often you consume it, as well as how your body breaks it down. Active cannabis ingredients like THC are stored in body fat. This means that they’ll stay in your system longer if you frequently consume cannabis or have a higher percentage of body fat. 

When it comes to drug testing, exactly how long cannabis is detectable in your body depends on the type of test. 

THC isn’t FDA approved to treat anxiety, but some people do find relief from anxiety with THC. If you’re new to cannabis, it’s a good idea to start with a lower dose. While everyone responds differently to THC, too much THC can lead to unpleasant side effects like anxiety and paranoia in some people.

Inhaled products take effect quickly, but they don’t last as long. Edibles can take hours to start working, but they last a long time. So, a 10 mg pre-roll or joint may feel stronger at first. But a 10 mg edible will likely feel stronger over time. Keep in mind that it’s best to start slowly and with a low dose (under 2.5 mg) to better understand how THC affects you.

The bottom line

There’s no one-size-fits-all dosage of THC. A safe and helpful dose for you will depend on many things, including your health and your reason for using it. And THC is in many different products — from edibles and THC-infused beverages to smokable cannabis. So the “right” dose also depends on how you consume it.

While there’s no specific dosage guidance for personal-use THC, it’s a good idea to follow the general guideline of starting low and slow. Speak with your healthcare team before taking cannabis products, especially if you’re taking other medications.

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Why trust our experts?

Alex Eastman, PhD, RN, is a California-based registered nurse and staff medical editor at GoodRx, where he focuses on clinical updates and Latino health.
Karen Hovav, MD, FAAP, has more than 15 years of experience as an attending pediatrician. She has worked in a large academic center in an urban city, a small community hospital, a private practice, and an urgent care clinic.

References

GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.

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