The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Joint pain (8-17%)
- Injection site pain (12%)
- Nausea (10-11%)
- Hot flash (7-11%)
- Fatigue (8-11%)
Please note: These side effects were reported in clinical trials by people who received [[EDITOR|DRUG_DISPLAY_NAME]] 500 mg monthly only. Your side effects can differ if you’re receiving [[EDITOR|DRUG_DISPLAY_NAME]] with other medications.
Less Common Side Effects
- Headache
- Back pain
- Muscle pain
- Bone pain
- Pain in the hands and feet
Source: DailyMed
The following Fulvestrant side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur:
More common
Black, tarry stools
bleeding gums
bloating or swelling of the face, arms, hands, lower legs, or feet
blood in the urine or stools
burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
chest pain or tightness
chills
cloudy urine
difficulty breathing
fainting
hoarseness
irregular heartbeat, recurrent
lower back or side pain
painful or difficult urination
pale skin
pinpoint red spots on the skin
rapid weight gain
sores, ulcers, or white spots on the lips or in the mouth
tender, swollen glands in the neck
tingling of the hands or feet
trouble with swallowing
troubled breathing with exertion
unusual bleeding or bruising
unusual tiredness or weakness
unusual weight gain or loss
Less common
confusion
dizziness or lightheadedness
fast heartbeat
mood or mental changes
muscle cramps in the hands, arms, feet, legs, or face
numbness and tingling around the mouth, fingertips, or feet
pain in the chest, groin, or legs, especially the calves
pain, redness, or swelling in the arm or leg
seizures
severe, sudden headache
slurred speech
stomach cramps
sudden loss of coordination
sudden, severe weakness or numbness in the arm or leg
vision changes
Incidence not known
Dark urine
flushing or redness of the skin
general feeling of tiredness or weakness
headache
hives or welts, itching, skin rash
large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals
light-colored stools
stomach pain, continuing
upper right abdominal pain
vaginal bleeding
vomiting
yellow eyes or skin
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Back pain
bladder pain
body aches or pain
bone pain
change in or loss of taste
decreased appetite
difficulty having a bowel movement
difficulty with moving
dryness or soreness of the throat
feeling of warmth or heat
feeling sad or empty
frequent urge to urinate
general feeling of discomfort or illness
hair loss or thinning of hair
irritability
joint pain
lack or loss of appetite
lack or loss of strength
loss of interest or pleasure
muscle aches and pains
muscle stiffness
pain at the injection site
pain in the arms or legs
pelvic pain
shivering
stomach pain
sudden sweating
trouble concentrating
voice changes
Incidence not known
Feeling of constant movement of self or surroundings
sensation of spinning
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

