provider image
Welcome! You’re in GoodRx for healthcare professionals. Now, you’ll enjoy a streamlined experience created specifically for healthcare professionals.
Skip to main content
Febuxostat Coupon - Febuxostat 40mg tablet

febuxostat

Generic Uloric
Used for Gout
Used for Gout

Febuxostat (Uloric) is a once daily medication that can prevent gout flares. It's a second-choice treatment option after allopurinol (Zyloprim).

Last reviewed on September 16, 2021
basics-icon

What is Febuxostat (Uloric)?

What is Febuxostat (Uloric) used for?

  • Gout in people who can't take or haven't responded to allopurinol (Zyloprim)

How Febuxostat (Uloric) works

Febuxostat (Uloric) stops an enzyme called xanthine oxidase from making uric acid; this then lowers the uric acid levels in your body. Keeping uric acid levels low can prevent gout attacks and kidney stones.

Drug Facts

Common BrandsUloric
Drug ClassAntigout
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only
coupon-save-icon

Get your GoodRx coupon

Avg retail price
$225.29(save 90.23%)
GoodRx discount
$22.00
See prices
basics-icon

What are the side effects of Febuxostat (Uloric)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Change in liver labs (5-7%)
  • Rash (1-2%)
  • Nausea (1%)
  • Joint pain (1%)

Other Side Effects

  • Ringing in the ear and hearing problems
  • Blurry vision
  • Vomiting
  • Upset stomach and stomach pain
  • Gas
  • Heartburn
  • Stomach ulcers
  • Change in taste and appetite
  • Dehydration
  • Low blood cells
  • Change in labs
  • Muscle pain and stiffness
  • Anxiety
  • Trouble sleeping, insomnia
  • Mood changes
  • Change in hair growth and color
  • Cold and flu-like symptoms

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Serious skin reaction: red, swollen, blistered, or peeling skin
  • Liver problems: yellowing of the skin or eyes, nausea, vomiting, stomach upset, dark urine, itchiness
  • Chest pain

Source: DailyMed

The following side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Rare

Arm, back, or jaw pain

black, tarry stools

bloody nose

blurred vision

chest pain or discomfort

chills

cloudy urine

confusion

cough

dark urine

decreased frequency or amount of urine

diarrhea

difficult or labored breathing

difficulty with moving

dizziness

dry mouth

fainting

fast, irregular, pounding, or racing heartbeat or pulse

feeling of fullness

fever

gaseous abdominal or stomach pain

general feeling of tiredness and weakness

headache

heavier menstrual periods

inability to speak

increase in heart rate

increased thirst

itching, skin rash

joint pain, stiffness, or swelling

large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals

lightheadedness

loss of appetite

loss of bladder control

muscle aching or cramping

nausea

nervousness

pain, swelling, or redness in the joints

painful or difficult urination

pale skin

pinpoint red spots on the skin

pounding in the ears

rapid breathing

redness of the skin

right upper abdominal or stomach pain and fullness

runny nose

seizures

severe or sudden headache

shivering

slow or fast heartbeat

slurred speech

sore throat

sores, ulcers, or white spots on the lips or in the mouth

stomach fullness or pain

sunken eyes

sweating

swelling

temporary blindness

thirst

tightness in the chest

trouble sleeping

trouble swallowing

unusual bleeding or bruising

unusual tiredness or weakness

vomiting

vomiting of blood or material that looks like coffee grounds

weakness in the arm or leg on one side of the body, sudden and severe

weight gain

wrinkled skin

yellow eyes and skin

Incidence not known

Blistering, peeling, or loosening of the skin

diarrhea

difficulty with swallowing

hives

hoarseness

lower back or side pain

muscle cramps or spasms

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

red skin lesions, often with a purple center

red, irritated eyes

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Rare

Anxiety

bad, unusual, or unpleasant (after) taste

blistering, crusting, irritation, itching, or reddening of the skin

body aches or pain

breast pain

bruising

burning feeling in the chest or stomach

burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

change in taste

changes in hair color

constipation

continuing ringing or buzzing or other unexplained noise in the ears

cough producing mucus

cracked, dry, or scaly skin

decrease in smell

decreased interest in sexual intercourse

deep or fast breathing with dizziness

depression

ear congestion

excess air or gas in the stomach or bowels

feeling of constant movement of self or surroundings

fruit-like breath odor

gum pain

hair loss or thinning of the hair

hearing loss

heartburn

inability to have or keep an erection

inability to move the arms and legs

increased or decreased appetite

increased sensitivity of the skin to sunlight

increased sweating

increased urination

irritability

large, flat, blue, or purplish patches in the skin

loss in sexual ability, desire, drive, or performance

loss of consciousness

loss of voice

muscle or bone pain or stiffness

muscle spasm, tightness, or weakness

muscle twitching

nasal congestion

numbness of the feet, hands, and around the mouth

painful blisters on the trunk of the body

pains in the stomach, side, or abdomen, possibly radiating to the back

sensation of spinning

severe or continuing stomach pain

severe sunburn

shakiness in the legs, arms, hands, or feet

skin rash, encrusted, scaly, and oozing

sleepiness or unusual drowsiness

small red or purple spots on the skin

sneezing

stomach discomfort, upset, or pain

sudden numbness and weakness in the arms and legs

sweating

swelling of the breasts or breast soreness in both females and males

throat irritation

trembling or shaking of the hands or feet

trouble sleeping

unexplained weight loss

unusual drowsiness, dullness, or feeling of sluggishness

weight loss

Incidence not known

Aggressive thoughts

false beliefs that cannot be changed by facts

seeing, hearing, or feeling things that are not there

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

pros-and-cons

Pros and cons of Febuxostat (Uloric)

thumbs-up

Pros

Only needs to be take once a day

Available as a lower-cost generic medication

Less risk of kidney stones when compared to allopurinol (Zyloprim)

Taken once a day with or without food

Can be used in people with kidney or liver problems

thumbs-down

Cons

Can cause more gout flares when you first start

Not a good option for people with heart conditions

Should only be used if allopurinol (Zyloprim) isn't an option

Won't treat an acute gout attack

pharmacist-tips

Pharmacist tips for Febuxostat (Uloric)

pharmacist
  • Gout attacks might be more common when you first start febuxostat (Uloric). Continue to take febuxostat (Uloric) every day and use your as needed gout medications for the attacks/flares.

    • Try to take febuxostat (Uloric) at the same time every day. It doesn't matter if you take it with or without food.

      • Make sure you follow up with your provider and get labs drawn regularly. Lab work will show if the medication is working correctly.

        • Tell your provider about all the medications you're taking, including over-the-counter (OTC) medications and supplements. In fact, many medications can interact with febuxostat (Uloric). It can't be taken with some medications like azathioprine and mercaptopurine.

          faqs

          Frequently asked questions about Febuxostat (Uloric)

          Is febuxostat (Uloric) safer than allopurinol (Zyloprim)?
          There are some people who might be allergic to allopurinol (Zyloprim) or can't take it because they have severe kidney problems. Febuxostat (Uloric) can be a safer alternative for these individuals. For most people, however, febuxostat (Uloric) is not safer than allopurinol (Zyloprim) because of the risk for sudden heart-related death.
          Is febuxostat (Uloric) safe for my kidneys?
          Yes, febuxostat (Uloric) is safe for your kidneys and can be used safely in people with kidney problems.
          Can I take febuxostat (Uloric) during a gout attack?
          Febuxostat (Uloric) can help prevent a gout attack, not treat ones that are already happening. If you're in the middle of a gout attack, you should take a painkiller or colchicine (Colcrys) instead.
          How quickly does febuxostat (Uloric) work?
          Febuxostat (Uloric) starts working within a few hours to lower uric acid levels. In the beginning, you might experience more gout attacks so it might not feel like it's working. However, the gout attacks happen because your body is moving uric acid around to adjust for the lower levels of uric acid in the blood. Continue taking it every day so it can work properly to prevent gout attacks in the future.
          Can febuxostat (Uloric) be taken during pregnancy?
          There hasn't been any studies to determine whether febuxostat (Uloric) is safe during pregnancy. If you're pregnant or wanting to become pregant, talk to you provider to see if they think febuxostat (Uloric) will be safe for you.
          GoodRxEducationalIcon

          How to save using GoodRx

          Compare Prices
          1. Compare PricesSpecify your dosage and quantity to find out exactly how much you can save.
          Select your free coupon
          2. Select your free couponYou can use the displayed coupon, or compare prices at other pharmacies near you.
          Show coupon to your pharmacist
          3. Show coupon to your pharmacistPresent your printed or electronic coupon when you pick up your prescription.
          Get free couponLearn more
          warings-icon

          What are the risks and warnings for Febuxostat (Uloric)?

          Febuxostat (Uloric) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

          risk-warning

          Heart problems

          • Risk factors: Having a history of heart problems

            In clinical trials, there were more heart disease-related deaths in people taking febuxostat (Uloric) than in those taking allopurinol. For this reason, febuxostat (Uloric) should only be used if allopurinol doesn't work or can't be used. Let your provider know if you have a history of heart conditions and if you're taking preventative medications like aspirin. Get medical help right away if you have chest pain or a change in your heart beat.

            risk-warning

            More gout attacks

            Many people have more gout attacks during the first few weeks of taking febuxostat (Uloric). This might be caused by the changes in your uric acid levels. Your provider might prescribe another medication for you to take with febuxostat (Uloric) to help with the gout attacks in the beginning.

            risk-warning

            Liver damage

            Although rare, febuxostat (Uloric) can cause serious liver damage, which can be fatal (deadly) in some cases. Your provider will check your liver labs regularly and might stop the medication if your labs look abnormal. Let your provider know if you have any yellowing of the skin or eyes, as these can be signs of a liver problem.

            risk-warning

            Serious skin reaction

            • Risk factors: People who had a skin reaction after taking allopurinol (Zyloprim)

              In some rare cases, people have developed a severe skin reaction after taking febuxostat (Uloric). If you developed a skin reaction after taking allopurinol (Zyloprim), you might also be at risk for developing one with febuxostat (Uloric) too. Stop taking febuxostat (Uloric) and call your provider right away if you notice red, swollen, blistered, or peeling skin.

              dosage

              Febuxostat (Uloric) dosage forms

              The average cost for 30 tablets of 40mg of Febuxostat (Uloric) is $22.00 with a free GoodRx coupon. This is 90.23% off the average retail price of $225.29.
              tablet
              Tablet
              DosageQuantityPrice as low asPrice per unit
              40mg30 tablets$22.00$0.73
              80mg90 tablets$38.00$0.42

              Typical dosing for Febuxostat (Uloric)

              The recommended starting dose is 40 mg by mouth once a day. Your provider might raise your dose to 80 mg once a day if you still have high uric acid levels after a couple of weeks.

              interactions

              Interactions between Febuxostat (Uloric) and other drugs

              Febuxostat (Uloric) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Febuxostat (Uloric). Please note that only the generic name of each medication is listed below.

              Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

              Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

              drug-cost

              How much does Febuxostat (Uloric) cost?

              To access savings, use a GoodRx coupon and pay just a fraction of the retail price.View prices & coupons
              contraindications-icon

              Febuxostat (Uloric) contraindications

              Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Febuxostat (Uloric) will not be safe for you to take.
              alternatives

              What are alternatives to Febuxostat (Uloric)?

              There are a number of medications that your doctor can prescribe in place of Febuxostat (Uloric). Compare a few possible alternatives below.
              Febuxostat (Uloric)
              Used for:
              • Gout in people who can't take or haven't responded to allopurinol (Zyloprim)

              $22.00 Lowest GoodRx priceView Prices
              Used for:
              • Gout (joint pain and swelling caused by high uric acid levels)

              • Boosting antibiotic activity to fight infections

              $44.40 Lowest GoodRx priceView Prices
              Used for:
              $4.80 Lowest GoodRx priceView Prices
              images

              Febuxostat (Uloric) images

              Green Oval S And 284 - Febuxostat 40mg Tablet
              This medicine is Green, Oval Tablet Imprinted With "S" And "284".Green Oval S And 284 - Febuxostat 40mg Tablet
              Yellow Round Feb And 40 - Febuxostat 40mg Tablet
              This medicine is Yellow, Round Tablet Imprinted With "40" And "Feb".Yellow Round Feb And 40 - Febuxostat 40mg Tablet
              Green Round L 440 - Febuxostat 40mg Tablet
              This medicine is Green, Round Tablet Imprinted With "L 440".Green Round L 440 - Febuxostat 40mg Tablet
              Green Round F And 40 - Febuxostat 40mg Tablet
              This medicine is Green, Round Tablet Imprinted With "40" And "F".Green Round F And 40 - Febuxostat 40mg Tablet
              White Oval 401 - Febuxostat 40mg Tablet
              This medicine is White, Oval Tablet Imprinted With "401".White Oval 401 - Febuxostat 40mg Tablet

              Get savings updates for Febuxostat (Uloric)

              Receive price alerts, news, and other messages from GoodRx about Febuxostat (Uloric) and other healthcare topics and relevant savings offers.

              By signing up, I agree to GoodRx's Terms and Privacy Policy, and to receive marketing messages from GoodRx.

              Browse medications

              View All

              Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.