Beyaz is a combination birth control pill that contains 2 hormones — drospirenone (a progestin) and ethinyl estradiol (an estrogen) — along with levomefolate (a folic acid supplement). In addition to preventing pregnancy, Beyaz is FDA approved to treat premenstrual dysphoric disorder (PMDD), acne in those who have started their periods, and to help raise folate levels. The pill is taken by mouth once daily. Each 28-day pack contains 24 active hormone tablets and 4 placebo tablets. Common side effects include headache, abnormal bleeding, and breast tenderness.
Beyaz is a combination of two hormones, drospirenone (a progestin) and ethinyl estradiol (an estrogen). These two hormones work together to prevent pregnancy by:
Beyaz works to treat PMDD by balancing hormone levels to reduce symptoms like mood swings, irritability, and bloating.
Beyaz also treats acne by lowering testosterone levels. This leads to less oil production and clogged pores.
Additionally, Beyaz also contains levomefolate, a folic acid supplement that can help lower the risk of birth defects.
The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Pregnancy prevention, acne, folate supplementation:
PMDD:
Contact your healthcare provider immediately if you experience any of the following.
Side effects that you should report to your care team as soon as possible:
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
Although hair loss wasn't a common side effect of Beyaz in clinical studies, it might happen due to hormonal changes in your body. In general, combined birth control pills with testosterone-like progestins, such as norethindrone in Heather, are more likely to cause hair loss. Beyaz, which contains drospirenone, has a less testosterone-like effect and is less likely to cause hair loss. If you're concerned about hair changes, talk to your prescriber.
Though rare, a few people did report weight gain while taking Beyaz in clinical studies for PMDD. But it's unclear whether the weight gain was caused by the medication or other factors. In general, studies show that birth control pills are unlikely to cause weight gain. If weight gain happens, they are more likely due to water retention rather than an increase in body fat. Talk with your healthcare team if you're concerned about Beyaz and weight gain.
You can generally expect to have a withdrawal period every 28-day cycle, during the 4 days of taking placebo pills. But your periods might change, especially in the first few months after starting Beyaz. In clinical studies, some people taking Beyaz experienced heavier periods, while others missed periods. It's possible to miss a period while taking this birth control, even if you're not pregnant. If you're concerned about a missed period or changes in your menstrual bleeding, talk with your healthcare team.
If you take Beyaz at the same time every day without missing any pills, it's about 99% effective at preventing pregnancy. But if you miss a pill here and there, its success rate drops to about 91%. Be aware that your chance of getting pregnant is higher if you don’t follow your gynecologist’s direction or frequently miss doses. If you've trouble remembering to take your pill, consider setting an alarm or using a pill organizer to stay on track.
Beyaz contains 20 mcg of ethinyl estradiol. Talk with your healthcare team if you have more questions about the dose of estrogen in this medication
Yes, Beyaz is a low-dose birth control. In general, birth control pills that contain 20 mcg of ethinyl estradiol or less are considered to have low-dose estrogen.
Yes, Beyaz is a combination birth control pill. The active pills contain both drospirenone (a progestin) and ethinyl estradiol (an estrogen), which work together to prevent pregnancy, treat PMDD, and help with acne. But the placebo pills only contain levomefolate, a form of folic acid.
Beyaz and Yaz contain the same amount of drospirenone and ethinyl estradiol and are both approved to prevent pregnancy, treat PMDD, and help with acne. The main difference is that Beyaz also contains levomefolate (a form of folic acid), and Yaz doesn't. Folic acid is important for reducing the risk of birth defects, so Beyaz might be a good option if you plan to get pregnant soon after stopping birth control or if you accidentally become pregnant while taking it. Talk with your gynecologist if you have questions about how they both compare.
Beyaz can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Smoking cigarettes while using Beyaz can significantly raise your risk for blood clots. These blood clots can lead to more serious problems, such as heart attack and stroke. The risk is greater if you're over 35 years old and have a history of smoking cigarettes. If you smoke, talk with your gynecologist about safer birth control alternatives.
Beyaz can raise the risk of serious blood clots because it contains ethinyl estradiol (an estrogen). Higher estrogen levels can lead to more blood proteins that stimulate clot formation. Some studies also suggest that birth control pills with drospirenone, like Beyaz, might have a higher risk of blood clots compared to pills with levonorgestrel or other progestins. These clots can be life-threatening and can form anywhere in your body. Get medical attention right away if you have any signs or symptoms of a blood clot:
Your risk of blood clots is higher if you're older, smoke cigarettes, or have certain medical conditions. It also increases if you're on bedrest after surgery or have just given birth. Your gynecologist will usually stop Beyaz 3 to 4 weeks before surgery and restart it 2 weeks after to lower your risk. If you recently delivered a baby, you should wait at least 4 weeks after delivery to start this medication, and only if you aren't breastfeeding. Talk with your gynecologist if you have any questions regarding your risk of blood clots.
Beyaz contains drospirenone, which can cause high levels of potassium in some people. Taking Beyaz with medications that raise potassium levels like ACE inhibitors, potassium-sparing diuretics, or potassium supplements can put you more at risk. Your gynecologist might monitor your potassium levels during your first cycle of Beyaz and periodically while you're taking it. Contact your health care team if you experience signs of high potassium like nausea, irregular heartbeat, or muscle weakness.
Study results are mixed, but Beyaz and other combined hormonal birth control pills might raise your risk for breast and cervical cancer.
Don't take Beyaz if you currently have or have had breast cancer because some types of breast cancer grow faster in the presence of estrogen, which is in this medication. Perform breast self-checks regularly at home and get yearly breast exams with your gynecologist to help with early detection. Let them know if you notice any new or abnormal lumps, pain, or swelling in your breasts.
Make sure you follow up with your gynecologist to get proper screenings for cervical cancer. Report any signs of vaginal bleeding or discharge that's not normal.
Don't use Beyaz if you have liver problems, such as hepatitis, severe cirrhosis, or liver tumors. Although rare, this medication can raise your risk of benign liver tumors. If you notice signs of liver problems, stop using Beyaz and talk to your gynecologist about other birth control options. Signs of liver problems include jaundice (yellowing of the skin or whites of the eyes), fever, tiredness, loss of appetite, or dark urine..
Some studies suggest that Beyaz can raise the risk of gallbladder disease since more progestin and estrogen can lead to higher chance of gallstones. Although the risk is low, talk to your gynecologist if you have a history of gallbladder disease before starting this medication.
Beyaz can raise your blood pressure. The risk is higher if you're older and have been using birth control for a long time. If you have a history of high blood pressure that's well-controlled, your prescriber might monitor you while you use Beyaz. If you have concerns, talk with them about the risks and benefits of using this medication.
Beyaz can raise your blood sugar and triglycerides levels. If you have prediabetes or diabetes, your prescriber will likely monitor your blood sugar while you take this medication. High triglycerides can lead to a higher risk of pancreatitis (inflammation of the pancreas). Speak with your gynecologist before starting Beyaz if you have a history of high blood sugar or triglycerides. They might suggest a different birth control option or monitor your lab work more closely while you're using this medication.
Let your gynecologist know if you experience new or worsening migraines or headaches while using Beyaz. If you develop frequent, severe, or new headaches, you might need to stop the medication.
People who take Beyaz can sometimes experience irregular bleeding and spotting, especially during the first 3 months of taking this medication. Irregular bleeding can vary from slight staining to bleeding similar to a regular period. This problem is often temporary, so continue taking your medication as directed. If your bleeding doesn't stop, becomes heavier, or you miss a period after the initial bleeding, let your gynecologist know. Your gynecologist can perform blood tests to rule out pregnancy or other potential causes for bleeding.
If you have a history of depression, your prescriber will monitor you while using Beyaz. If your depression gets worse or becomes serious, they might stop the medication. Let your prescriber know if you experience mood changes, sadness, or loss of interest in activities while taking this medication.
If you have certain conditions, such as hereditary angioedema or chloasma (a skin condition that causes dark patches on the face), talk to your prescriber before taking Beyaz because it might worsen your symptoms. If you have a history of chloasma, limit exposure to the sun or UV light while taking Beyaz.
| Dosage | Quantity | Price as low as | Price per unit |
|---|---|---|---|
| 28 tablets | 1 package | $49.07 | $49.07 |
Beyaz comes in a 28-day pack, which contains 24 active hormone tablets and 4 placebo tablets. Each active tablet contains 3 mg drospirenone and 20 mcg ethinyl estradiol. Each placebo tablet contains 0.451 mg levomefolate calcium.
Follow your prescriber's instructions on how to take this medication. The tablets must be taken in order as shown on the packaging.
The typical dose is 1 active tablet by mouth daily for 24 days, followed by 1 placebo tablet daily for the remaining 4 days.
Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Beyaz will not be safe for you to take.