The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
Up to 9% of people who used diflunisal experienced the following side effects:
- Nausea
- Heartburn
- Stomach pain
- Diarrhea
- Rash
- Headache
Less Common Side Effects
- Vomiting
- Constipation
- Passing gas
- Sleepiness
- Tiredness
- Difficulty falling asleep
- Dizziness
- Ringing in the ear
Diflunisal serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Heart attack: dizziness, tiredness, cold sweat, trouble breathing, chest pain or tightness, anxiety
- Stroke: tiredness, lightheadedness, blurred vision, difficulty speaking, difficulty walking, weakness on one side of the body
- Stomach bleeds: blood in your vomit, stool that looks like black coffee grounds, pain in your stomach that doesn't go away
- Heart failure: trouble breathing, tiredness, swelling in your body, sudden weight gain
- Liver damage: fever, chills, fatigue, nausea, vomiting, yellowing of the skin or whites of the eyes, clay-colored stool, and dark urine
- Severe asthma attack: chest pain, cough, difficulty breathing, wheezing
- Serious allergy and skin reaction: fever, rash, body aches, cough, swelling of the face, peeling skin, painful blisters all over your body
Source: DailyMed
The following Diflunisal side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common
Stomach cramps or pain
Less common
Back or leg pains
bleeding gums
blistering, peeling, loosening of skin
bloody or black, tarry stools
bloody or cloudy urine
blurred or loss of vision
burning feeling in chest or stomach
burning while urinating
clay-colored stools
cough or hoarseness
cracks in the skin
dark-colored urine
difficult or painful urination
difficulty breathing
difficulty swallowing
disturbed color perception
dizziness
double vision
facial swelling
fast heartbeat
feeling of warmth
fever with or without chills
flu-like symptoms
general body swelling
general feeling of tiredness or weakness
greatly decreased frequency of urination or amount of urine
halos around lights
headache
increased blood pressure
increased thirst
indigestion
joint or muscle pain
large, hive-like swelling on face, eyelids, lips, tongue, throat, hands, legs, feet, sex organs
light-colored stools
liver function abnormalities
loss of appetite
loss of heat from the body
lower back or side pain
muscle aches, pains, or weakness
nausea or vomiting
night blindness
noisy breathing
nosebleeds
overbright appearance of lights
pale skin
pinpoint red spots on skin
puffiness or swelling of the eyelids or around the eyes, face, lips or tongue
red, irritated eyes
redness of the face, neck, arms and occasionally, upper chest
red skin lesions, often with a purple center
red, swollen skin
severe or continuing stomach pain
shortness of breath
skin rash
sores, ulcers, or white spots in mouth or on lips
stomach upset
swelling of face, fingers, feet or lower legs
swollen lymph nodes
tenderness in stomach area
tightness in chest
troubled breathing
tunnel vision
unpleasant breath odor
unusual bleeding or bruising
unusual tiredness or weakness
upper right abdominal pain
vomiting of blood or material that looks like coffee grounds
yellow eyes or skin
Symptoms of overdose
Change in consciousness
confusion about identity, place, and time
continuing ringing or buzzing or other unexplained noise in ears
decreased awareness or responsiveness
deep or fast breathing with dizziness
fast, pounding, or irregular heartbeat or pulse
hearing loss
loss of consciousness
numbness of feet, hands, and around mouth
severe sleepiness
sweating
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common
Bloated, full feeling
burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
discouragement
dry mucous membranes
excess air or gas in stomach or intestines
feeling of constant movement of self or surroundings
feeling sad or empty
increased sensitivity of skin to sunlight
irritability
lack or loss of strength
lightheadedness
loss of interest or pleasure
mood or mental changes
nervousness
passing gas
seeing, hearing, or feeling things that are not there
sensation of spinning
severe sunburn
swelling or inflammation of the mouth
tiredness
trouble concentrating
trouble sleeping
unable to sleep
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
