DEFIBROTIDE treats veno-occlusive disease (VOD), a condition that occurs when blood vessels in the liver become blocked. This decreases blood flow, which can cause liver injury. It works by helping your body break down blood clots. It also helps prevent new clots from forming. Get Defitelio for as low as $1,176.30, save up to 80% off the average retail price for the most common version, by using a GoodRx coupon.