Skip to main content
Heart Failure

Heart Failure With Preserved Ejection Fraction, Explained

Lauren Smith, MASanjai Sinha, MD
Written by Lauren Smith, MA | Reviewed by Sanjai Sinha, MD
Updated on October 4, 2025
Featuring Marrick Kukin, MDReviewed by Sanjai Sinha, MD | October 4, 2025

If you are having symptoms like fatigue and shortness of breath with minimal physical activity, your doctor may consider heart failure. One of the numbers they’ll want to measure is something called ejection fraction. However, even if your ejection fraction comes back “normal,” you might still have heart failure. This type is known as heart failure with preserved ejection fraction.

Ejection fraction is the percentage of blood that gets pumped out of the left ventricle with each beat. The left ventricle is one of four chambers of the heart. It’s the last chamber that oxygen-rich blood goes through before dispersing throughout the body.

References

GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.

why trust our exports reliability shield

Why trust our experts?

Lauren Smith, MA
Written by:
Lauren Smith, MA
Lauren Smith, MA, has worked in health journalism since 2017. Before joining GoodRx, she was the senior health editor and writer for HealthiNation.
Sanjai Sinha, MD
Reviewed by:
Sanjai Sinha, MD
Sanjai Sinha, MD, is a board-certified physician with over 20 years of experience. He specializes in internal medicine.

Was this page helpful?

Latest articles