Do You Have a Sinus Infection or COVID-19?

Upper respiratory infections are common, especially during the cooler months. Now that COVID-19 has joined the landscape, it’s even more challenging to figure out what’s making you sick.

Sinus infections are particularly confusing. They often start as a common cold and can be slow to get better over time. Sometimes, they even need treatment with antibiotics. But there are some important differences. 

What’s the difference between COVID and a sinus infection?

A sinus infection (sinusitis) occurs when viruses or bacteria cause inflammation and fluid buildup inside your sinuses. Sinuses are the hollow spaces in the bones of your face. Adults have sinuses behind their cheeks, nose, and forehead. Usually, these spaces are filled with air. When you have a sinus infection, these areas get filled with mucus instead of air, leading to painful pressure. 

COVID is an infection caused by the SARS-CoV-2 coronavirus. When the virus infects you, it multiplies throughout your body. COVID can cause symptoms that range from mild to severe. Omicron subvariants of COVID can cause symptoms that resemble the common cold and other upper respiratory infections more than ever before.

Which symptoms do COVID and sinus infections share?

Both COVID and sinus infections are upper respiratory infections. Both can cause:

• Cough

• Headache

• Runny or stuffy nose

• Sore throat

• Fever

Below is a chart showing the difference in symptoms between COVID and sinus infection.

Symptoms unique to sinus infections

By definition, sinus infections happen inside the sinuses. So, when you have a sinus infection, your symptoms come from that location. But the inflammation and drainage of sinusitis can sometimes lead to problems elsewhere. 

Face pain and pressure are the hallmarks of a sinus infection. Nasal congestion is also very common. People with COVID illness can experience a runny nose or congestion as well, but not as often as with a sinus infection. 

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• Cold vs. sinus infection: Learn the best way to figure out if you have a cold or a sinus infection.

Sinus infections tend to cause:

• A feeling of pressure inside the face, like pain behind the eye, cheek pain, or an intense headache

• Nasal congestion

• Runny nose

• Pain in the teeth

And, when you have a sinus infection, the drainage of mucus down your throat can cause: 

• Wet cough

• Sore throat

• Upset stomach or nausea 

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Symptoms unique to COVID

COVID infection is more generalized than a sinus infection. When you have COVID illness, the virus infects cells in different areas of the body. Because of this, COVID can cause a variety of symptoms, many of which might seem unrelated to each other. 

In comparison to sinusitis, COVID is more likely to cause lung-related symptoms, especially a cough. You’re also more likely to have a fever with COVID. Loss of taste or smell is another symptom that’s more common with COVID. 

Other symptoms that are more likely with COVID versus sinusitis include:

• Dry cough

• Trouble breathing or shortness of breath

• Chest pain

• Fatigue

• Muscle or body aches

• Stomach ache or diarrhea

Keep in mind that COVID symptoms aren’t always predictable. Some people don’t have any symptoms at all: They’re known as “asymptomatic carriers.” In other people, symptoms get worse quickly and need emergency care.

How do you know if your loss of smell or taste is from COVID or a sinus infection?

In the early stages of the COVID pandemic, losing your sense of smell or taste usually meant you had COVID infection. But once Omicron subvariants came onto the scene, loss of smell became much less frequent. 

Some studies suggest that just over 10% of people now lose their sense of smell with COVID infection. So, it can be trickier to use this symptom to tell COVID apart from a sinus infection. That’s because sinus infections are also a common cause of losing your sense of smell.

Here’s one thing to keep in mind: If a sinus infection causes your loss of smell, it’s usually because of local inflammation and congestion in your nose. So, you’ll probably also have a runny nose and nasal congestion. With COVID, you can lose your sense of smell even without having any nasal symptoms. 

How else can you tell a sinus infection and COVID apart?

The best way to tell the difference between sinusitis and COVID is to take a COVID test. 

An at-home rapid antigen test can usually give you an answer within 15 minutes. But it’s important to know that rapid tests can give a false negative result. This means that the test is negative when you actually do have COVID infection. For this reason, the FDA recommends repeating a COVID test 48 hours later if you have symptoms and your first test is negative. 

The timing of your symptoms can help you tell apart a sinus infection from COVID too. 

Most sinus infections start with a viral cold. After a few days of mild cold symptoms, the fever and head or face pressure of a sinus infection become noticeable. Symptoms often get worse after 7 to 10 days. In fact, sinus infections usually aren’t diagnosed or treated until symptoms have been around for 10 to 14 days.

By contrast, COVID symptoms usually get better after 7 to 10 days. But the pattern of symptoms may be different with each variant. And while breathing symptoms are less common with COVID now than they were, they’re still more likely with COVID than with sinusitis. 

Can COVID turn into a sinus infection, or vice versa?

Yes, COVID could lead to a sinus infection. Sinuses can become inflamed due to a viral respiratory infection like COVID. When there’s increased mucus production and congestion that lingers, this makes it more likely for sinusitis to develop. But a sinus infection can’t cause a COVID infection. You need to be exposed to the COVID virus to develop symptoms.

What can you do to lower your risk of getting COVID or a sinus infection?

The best way to prevent COVID is to get vaccinated and stay up-to-date on your vaccines. 

You can lower your chances of catching a sinus infection by practicing good hygiene, just like you would to avoid getting a cold or the flu. These strategies will help lower your risk of catching COVID as well. 

Here are some steps you can take: 

• Wash your hands frequently.

• Keep your distance from people who are sick.

• Avoid touching your eyes, nose, and mouth with unwashed hands. 

• Consider wearing a mask when in a crowded indoor setting during times of high respiratory disease activity.

What to do if you’re not sure whether you have a sinus infection or COVID

COVID is very contagious, so you’ll want to know if you have it. Even if your symptoms are mild, you could spread it to others. And they might not be so lucky with their illness. That’s why taking a COVID test is a good idea when you get sick, especially if you could’ve been exposed to others with COVID. 

Keep in mind that COVID testing is helpful, but it’s not perfect. For example, a test might not pick up a COVID infection that’s just getting started. If your COVID test result is negative and you’re feeling OK, it’s reasonable to treat your symptoms at home with over-the-counter (OTC) remedies for a few days. 

After 3 or 4 days, your symptoms — including fever — should begin to improve on their own. If that’s not happening, and especially if things are getting worse, it’s time to make an appointment with a healthcare professional. 

Many viral sinus infections will go away on their own. If you have a bacterial sinus infection, it may require antibiotics. If your symptoms are worsening or just don’t seem to be getting better, let a healthcare professional know. Of course, if you develop difficulty breathing, chest pain, or shortness of breath, you should get medical attention right away.

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Written by:

Kerry R. McGee, MD, FAAP

Kerry McGee, MD, FAAP, has over a decade of experience caring for babies, children, and teenagers as a primary care pediatrician. She has a special interest in adolescent health, particularly in adolescent mental health.

Edited by:

Karla Robinson, MD

Karla Robinson, MD, is a medical editor for GoodRx. She is a licensed, board-certified family physician with almost 20 years of experience in health through varied clinical, administrative, and educational roles.

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