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Ankylosing Spondylitis

How Non-Radiographic Axial Spondyloarthritis (nr-axSpA) Is Diagnosed

Brittany DoohanSanjai Sinha, MD
Written by Brittany Doohan | Reviewed by Sanjai Sinha, MD
Updated on October 7, 2025
Featuring Magdalena Cadet, MDReviewed by Sanjai Sinha, MD | October 7, 2025

Non-radiographic axial spondyloarthritis (nr-axSpA), is a type of inflammatory arthritis that primarily affects the spine. It falls under the umbrella of spondyloarthritis, a category of arthritis diseases that affect the spine.

Chronic back pain is the hallmark symptom of nr-axSpA, but it’s a bit different than other types of back pain. The onset of pain is often gradual and occurs in people under 45 years of age, and the occurrence of the pain is often worse in the morning and better after exercise. People with nr-axSpA may experience pain and inflammation in other parts of their body as well. Learn more about the symptoms of nr-axSpA.

References

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Brittany Doohan
Written by:
Brittany Doohan
Brittany Doohan was the Content Director at HealthiNation and is currently the Editorial Director at Medscape. Through her work with Medscape, she won a Silver Telly Award in May 2022 for "Sleepless Nation: A Public Health Epidemic — Episode 2: A Decade Without a Diagnosis." She has worked in health journalism and video production for more than 8 years, and loves the challenge of explaining complex topics in an easy-to-understand and creative way.
Sanjai Sinha, MD
Reviewed by:
Sanjai Sinha, MD
Sanjai Sinha, MD, is a board-certified physician with over 20 years of experience. He specializes in internal medicine.

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