Compare Scopolamine vs. Compro
Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Scopolamine (Transderm Scop) and prochlorperazine (Compro) are both prescription medications used to treat nausea and vomiting, but they have some key differences. Scopolamine is an anticholinergic that comes as a patch applied behind the ear, while prochlorperazine is a phenothiazine available as a rectal suppository. Scopolamine is typically used to prevent nausea and vomiting from motion sickness or surgery, whereas prochlorperazine is used for severe nausea and vomiting. Scopolamine works by blocking acetylcholine in the brain, while prochlorperazine blocks dopamine. Scopolamine patches can be worn for up to 3 days, but they can cause side effects like dry mouth and dizziness. Prochlorperazine suppositories need to be inserted twice daily and can cause serious side effects like uncontrolled muscle movements and extreme sleepiness. Neither Scopolamine nor prochlorperazine are recommended for children under 18, but prochlorperazine must not be used in children under 2 years old or under 20 pounds. Both medications are available in generic forms, making them more affordable options.
- Scopolamine (Transderm Scop)Prochlorperazine (Compro)
- Scopolamine (Transderm Scop)Prochlorperazine (Compro)
Summary of Scopolamine vs. Compro
Summary for AnticholinergicPrescription onlyScopolamine (Transderm Scop) is a prescription anticholinergic medication. It's used to prevent nausea and vomiting from motion sickness, as well as from anesthesia or pain medications used in surgery. Scopolamine (Transderm Scop) comes as a patch that you place behind your ear. You need to apply it at least 4 hours before any activities that might cause motion sickness, or the night before your surgery. Common side effects scopolamine (Transderm Scop) include dry mouth, sleepiness, and dizziness.
Summary for PhenothiazinePrescription onlyProchlorperazine (Compro) rectal suppository is a typical antipsychotic. It's FDA-approved to treat severe nausea and vomiting in adults. But prochlorperazine (Compro) isn't a first-choice antiemetic because it can cause serious side effects, such as extreme sleepiness and uncontrolled muscle movements. While prochlorperazine (Compro) is a good option for people who can't take medications by mouth, some people might find it unpleasant or difficult to use because it needs to be inserted into the rectum, typically twice daily. Prochlorperazine (Compro) comes as a brand-name and generic medication.
Indications of Scopolamine vs. Compro
Indications for•Prevention of nausea and vomiting due to:Indications for•Severe nausea and vomitingPros and Cons of Scopolamine vs. Compro
Pros and Const for AnticholinergicPros•Works well for preventing nausea and vomiting•Effects lasts for up to 3 days•Applied to skin, so a good choice for people who've trouble taking pills•Available as a lower-cost genericCons•Not for use in children younger than 18 years old•Takes about 4 hours to start working, so need to remember to take it ahead of time•Doesn't treat nausea and vomiting that's already happening•Can cause drowsiness, blurry vision, and confusionPros and Const for PhenothiazinePros•Good option for people who have a hard time swallowing pills•Available as a generic medication•More convenient storage compared to some other suppositories because it doesn't need to be refrigeratedCons•Might be hard for some people to insert the suppository•Not recommended for use in children•Might cause rare but permanent side effects, such as uncontrolled muscle movementsCommon Side Effects of Scopolamine vs. Compro
Common Side Effects for•Dry mouth (29%)•Dizziness (12%)•Sleepiness (8%)•Agitation (6%)•Changes in vision (5%)Common Side Effects for•Drowsiness•Dizziness•Absent menstrual periods•Blurry vision•Low blood pressureWarnings of Scopolamine vs. Compro
Common Side Effects for•Angle-closure glaucoma•Brain and mental health problems•Risk of seizures in pregnant people with preeclampsia•Blockage in the stomach, intestines, or bladder•Withdrawal•Blurry vision•Skin burn from magnetic resonance imaging (MRI)Common Side Effects for•Higher risk of death in older adults with dementia-related psychosis•Difficulty controlling muscle movements (tardive dyskinesia)•Other conditions with uncontrolled muscle movements (dystonia, Parkinsonian symptoms, and restlessness)•Neuroleptic malignant syndrome (NMS)•Cover up more serious health problems•Higher risk of infections•Higher risk of falls•Liver problems•Seizures•High prolactin levels•Difficulty maintaining normal body temperaturePrices with our coupons for Scopolamine vs. Compro
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