Key takeaways
Myfortic (mycophenolic acid) and Rapamune (sirolimus) are both immunosuppressants used to prevent kidney transplant rejection, but they have some key differences. Myfortic is taken twice a day, while Rapamune is usually taken once a day. Myfortic is specifically for kidney transplants, whereas Rapamune can also treat lymphangioleiomyomatosis (LAM), a condition affecting the lungs, kidneys, and lymphatic system. Myfortic must be taken on an empty stomach, but Rapamune can be taken with or without food, as long as you are consistent. Myfortic is available in a generic form, which can be less expensive, and is suitable for children aged 5 and older. In contrast, Rapamune is not recommended for children under 12 and can cause fertility problems. Both medications have serious side effects, including risks of cancer and infections, and should not be used during pregnancy.
