Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Atorvastatin (Lipitor) and Lovastatin (Mevacor) are both statins used to lower cholesterol, but they have some key differences. Atorvastatin is a moderate-to-high intensity statin, meaning it can lower cholesterol levels more significantly than Lovastatin, which is a low-to-moderate intensity statin. Atorvastatin can be taken at any time of the day, while Lovastatin is typically taken in the evening with food. Both medications can cause muscle pain and a rare but serious condition called rhabdomyolysis, but muscle pain is less common with Lovastatin. Both medications are available as generics. But Atorvastatin also comes in a liquid form (Atorvaliq) for those who have trouble swallowing pills, whereas Lovastatin does not have a liquid option. Both medications should not be used during pregnancy or breastfeeding and require a prescription.
Atorvastatin (Lipitor)
Lovastatin
Atorvastatin (Lipitor)
Lovastatin
Summary of Lipitor vs. Mevacor
Summary for Statin
Prescription only
Atorvastatin (Lipitor) is a statin that helps lower cholesterol. As a moderate-to-high-intensity statin, it can lower cholesterol by a greater amount than many other statins. It can also help protect your heart health. The dosage is taken by mouth once a day. Atorvastatin tablets are available as brand-name Lipitor and a generic. There's also a liquid form that only comes as brand name Atorvaliq. It's possible to have side effects like muscle pain, joint pain, and stomach upset. Most times, atorvastatin (Lipitor) is taken along with a heart-healthy diet to get the most benefits from treatment.
Summary for Statin
Prescription only
Lovastatin is a low-to-moderate intensity statin that's taken once or twice per day. It's used to lower cholesterol in certain adults and children ages 10 years and older to help prevent heart attack or stroke. This medication lowers your "bad" cholesterol (LDL) and triglycerides (a type of fat) levels. It can also raise your "good" cholesterol (HDL). Follow a heart-healthy diet and get regular exercise while you're taking lovastatin so the medication can work as best as possible. Lovastatin side effects include stomach upset and headache.
•Helps lower "bad" cholesterol (LDL) and triglycerides (fats) and improve "good" cholesterol (HDL) levels
•Lowers the risk of problems caused by high cholesterol, like heart attack or stroke, in people with certain conditions (e.g., diabetes, high blood pressure)
•Available as a lower-cost generic
Cons
•Doesn't replace having a balanced diet and regular exercise routine to lower cholesterol levels
•Has more dosing limits for certain drug interactions than some other statins
•Not safe to use if you're pregnant or breastfeeding