Key takeaways
Furosemide (Lasix) and chlorthalidone (Thalitone) are both diuretics, but they belong to different classes and have some key differences. Furosemide is a loop diuretic, while chlorthalidone is a thiazide-like diuretic. Furosemide is typically used to relieve swelling from extra fluid and can also lower blood pressure, though it's not a first-choice option for high blood pressure. In contrast, chlorthalidone is primarily used to treat high blood pressure and can also help with swelling. Furosemide is usually taken once or twice daily, whereas chlorthalidone is taken once daily. Both medications can cause you to urinate more often, but furosemide starts working within an hour and lasts about 6 to 8 hours, while chlorthalidone takes about 2 to 3 hours to start working and can last up to 3 days. Additionally, both medications can cause dizziness and sensitivity to the sun, but chlorthalidone has a higher risk of causing gout attacks. Both are available in generic forms and should be taken with caution if you have a sulfa allergy.
