Compare Iqirvo vs. Livdelzi
Head-to-head comparisons of medication uses, side effects, warnings, and more.
- Iqirvo (elafibranor)Livdelzi (seladelpar)
- Iqirvo (elafibranor)Livdelzi (seladelpar)
Summary of Iqirvo vs. Livdelzi
Summary for Peroxisome proliferator-activated receptor (PPAR) agonistPrescription onlyIqirvo (elafibranor) has an accelerated approval from the FDA for treating primary biliary cholangitis (PBC) in adults. It works as a peroxisome proliferator-activated receptor (PPAR) agonist to help the body make less bile acid. But it’s not clear yet if the medication helps people with PBC live longer or helps the liver improve. Iqirvo (elafibranor) comes as an 80 mg tablet that's taken by mouth once per day. You can take Iqirvo (elafibranor) by itself or with ursodiol (Actigall). Side effects of Iqirvo (elafibranor) include weight gain, diarrhea, and stomach pain.
Summary for Peroxisome proliferator-activated receptor (PPAR)-delta agonistPrescription onlyLivdelzi (seladelpar) treats primary biliary cholangitis (PBC), a liver condition that happens when damaged bile ducts cause bile to build up. It’s a peroxisome proliferator-activated receptor (PPAR)-delta agonist that works to help the body make less bile acids. But it’s not clear yet whether it can slow liver damage in people with PBC. Livdelzi (seladelpar) is a tablet that’s taken once daily by mouth for adults. It’s taken either alone or with ursodiol (Actigall). Side effects of Livdelzi (seladelpar) include headache, dizziness, stomach pain, and bloating.
Indications of Iqirvo vs. Livdelzi
Indications for•Primary biliary cholangitis (PBC), a liver problem caused by damaged bile ductsIndications for•Primary biliary cholangitis (PBC), a liver condition due to damaged bile ductsPros and Cons of Iqirvo vs. Livdelzi
Pros and Const for Peroxisome proliferator-activated receptor (PPAR) agonistPros•Taken by mouth once per day•A good option if treatment with ursodiol (Actigall) isn't enough or if you can't take ursodiol (Actigall)•Helps improve levels of alkaline phosphatase (ALP), a liver enzyme that can be high with liver damageCons•Might cause muscle pain•Can raise the risk of bone fractures•Not known for sure if the medication helps people with PBC live longer or slow down liver damagePros and Const for Peroxisome proliferator-activated receptor (PPAR)-delta agonistPros•Taken once daily•Can help alleviate itching that’s associated with PBC•An option for people who haven’t responded well to other PBC treatments, like ursodiol (Actigall)Cons•Can cause headache, dizziness, stomach pain, and bloating•Can increase the risk of bone fractures•Not recommended for people with advanced liver cirrhosis (with symptoms like ascites, variceal bleeding, and loss of brain function)Common Side Effects of Iqirvo vs. Livdelzi
Common Side Effects for•Weight gain (23%)•Diarrhea (11%)•Stomach pain (11%)•Nausea (11%)•Vomiting (11%)•Joint pain (8%)•Constipation (8%)•Muscle pain (7%)•Broken bone (fracture, 6%)•Heartburn (6%)•Dry mouth (5%)•Weight loss (5%)•Rash (5%)Common Side Effects for•Headache (8%)•Stomach pain (7%)•Nausea (6%)•Bloating (6%)•Dizziness (5%)Warnings of Iqirvo vs. Livdelzi
Common Side Effects for•Muscle pain, weakness, and damage•Liver problems•Fractures•Risk of harm to a baby during pregnancy•Avoid in people with biliary obstructionCommon Side Effects for•Changes in liver function test results•Fractures•Avoid in people with biliary obstructionPrices with our coupons for Iqirvo vs. Livdelzi
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