Key takeaways
Iron/multivitamin (Integra, Ferralet 90) and Reblozyl (luspatercept) are both used to treat anemia, but they work in different ways and are used for different types of anemia. Iron/multivitamins are oral supplements that help your body make hemoglobin, which is needed to carry oxygen in your blood. They are mainly used to treat iron-deficiency anemia. Reblozyl, on the other hand, is an injectable biologic medication used for anemia in adults with beta thalassemia or certain myelodysplastic syndromes (MDS) who need regular red blood cell transfusions. While iron/multivitamins are typically taken daily, Reblozyl is given by a healthcare provider every three weeks. Iron/multivitamins can cause side effects like nausea and constipation, while Reblozyl may cause tiredness, headache, and muscle or joint pain. Additionally, iron/multivitamins can interact with medications like levothyroxine and ciprofloxacin, whereas Reblozyl requires monitoring for blood pressure and may increase the risk of harm to an unborn baby. Let your prescriber know if you are pregnant or considering becoming pregnant.
