Compare Integra vs. Reblozyl
Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Iron/multivitamin (Integra, Ferralet 90) and Reblozyl (luspatercept) are both used to treat anemia, but they work in different ways and are used for different types of anemia. Iron/multivitamins are oral supplements that help your body make hemoglobin, which is needed to carry oxygen in your blood. They are mainly used to treat iron-deficiency anemia. Reblozyl, on the other hand, is an injectable biologic medication used for anemia in adults with beta thalassemia or certain myelodysplastic syndromes (MDS) who need regular red blood cell transfusions. While iron/multivitamins are typically taken daily, Reblozyl is given by a healthcare provider every three weeks. Iron/multivitamins can cause side effects like nausea and constipation, while Reblozyl may cause tiredness, headache, and muscle or joint pain. Additionally, iron/multivitamins can interact with medications like levothyroxine and ciprofloxacin, whereas Reblozyl requires monitoring for blood pressure and may increase the risk of harm to an unborn baby. Let your prescriber know if you are pregnant or considering becoming pregnant.
- Multivitamin with ironReblozyl (luspatercept)
- Multivitamin with ironReblozyl (luspatercept)
Summary of Integra vs. Reblozyl
Summary for Iron supplementationPrescription onlyMultivitamin with iron is a combination multivitamin used to raise low iron levels. It comes in many different brands and formulations, including tablets, capsules, and chewable gummies. Make sure to read the manufacturer label of your multivitamin with iron product carefully to see what active ingredients it contains, since different brands can have different ingredients. Possible side effects of this supplement include nausea, constipation, and dark-colored stool.
Summary for BiologicPrescription onlyReblozyl (luspatercept or luspatercept-aamt) is an injectable medication used to treat anemia (low red blood cells) in adults with beta thalassemia or certain myelodysplastic syndromes (MDS) who require regular red blood cell transfusions. Reblozyl (luspatercept) is given by a healthcare provider every 3 weeks.
Indications of Integra vs. Reblozyl
Indications for•Iron supplementIndications for•Anemia in adults with beta thalassemia who require regular red blood cell (RBC) transfusions•Anemia in adults with myelodysplastic syndromes with ring sideroblasts (MDS-RS) or myelodysplastic/myeloproliferative neoplasms with ring sideroblasts and thrombocytosis (MDS/MPN-RS-T) who can't receive an erythropoiesis stimulating agent (ESA) and need regular RBC transfusionPros and Cons of Integra vs. Reblozyl
Pros and Const for Iron supplementationPros•Taken by mouth, typically once per day•Combines iron with multiple vitamins and supplements into one pill•Some brands, Novaferrum Multivitamin with Iron Pediatric Drops, are made specifically for childrenCons•Food might affect how well multivitamin with iron is absorbed in your body•Might cause nausea and constipationPros and Const for BiologicPros•Treatment is every 3 weeks•Can lower the need for RBC transfusions•Dose is individualized for each personCons•Not approved for children•Has to be given by injection•Can't give yourself the injection; must be given by a providerCommon Side Effects of Integra vs. Reblozyl
Common Side Effects for•Poor appetite•Nausea•Vomiting•Diarrhea•Constipation•Dark or black-colored stool•Stomach crampsCommon Side Effects for•Tiredness (14-41%)•Headache (14-26%)•Muscle or bone pain (20%)•Joint pain (19%)•Dizziness (11-18%)•Nausea (9-16%)•Diarrhea (12-16%)•Cough (14%)•Stomach pain (14%)•Difficulty breathing (13%)•Allergic reaction (10%)Warnings of Integra vs. Reblozyl
Common Side Effects for•Iron overdoseCommon Side Effects for•Blood clots•High blood pressure•Harm to unborn babyPrices with our coupons for Integra vs. Reblozyl
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