Head-to-head comparisons of medication uses, side effects, warnings, and more.
Comirnaty (Pfizer COVID-19 vaccine) is an mRNA vaccine that's used to prevent infection from the virus that causes COVID-19. It's FDA approved for people 65 years and older, and for children and adults ages 5 to 64 years old who have at least one risk factor for severe COVID. The vaccine is given as a single booster shot into the muscle by a healthcare professional. Common side effects include pain at the injection site, tiredness, headache, and chills.
Spikevax (Moderna COVID-19 vaccine) is an mRNA vaccine. It's used to prevent infection from the virus that causes COVID-19. Spikevax is FDA approved for people ages 65 years and older. It's also approved for people ages 6 months to 64 years with at least one risk factor for serious problems from COVID. This vaccine is given by a healthcare professional as an injection into the muscle. Most people only need 1 dose of the updated Spikevax booster shot for the year, except for babies who've never been vaccinated before. Side effects include pain at the injection site, muscle pain, and tiredness.
People 12 years and older:
People ages 5 to 11 years old:
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