The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Breast pain (25-31%)
- Menstrual cramps (20-21%)
- Headache (18-20%)
- Vaginitis (e.g., vaginal pain, itching, burning, or discharge; 6-13%)
- Weakness (8-12%)
- Breathing problems (7-12%)
- Irregular vaginal bleeding or other related menstrual issues (6-12%)
- Back pain (9-11%)
- Nausea (8-11%)
- Sore throat (4-10%)
Less Common Side Effects
- Application site reactions (e.g., irritation, itchiness, redness, swelling, rash, dry skin)
- Vaginal discharge
- General pain
- Stomach pain
- Diarrhea
- Indigestion or heartburn
- Passing gas
- Flu-like symptoms
- Runny nose
- Sinus infection
- Depression
- Trouble sleeping
- Nervousness
Combipatch serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Blood clot in arm or leg: swelling, pain, or tenderness in the arm or leg; skin that's warm to the touch
- Blood clot in the lung: trouble breathing, chest pain
- Heart attack: chest pain, arm pain, shortness of breath, cold sweat, lightheadedness
- Stroke: sudden weakness on one side of the body, drooping face, changes in your speech or vision, confusion, bad headache
- Severe allergic reaction: hives; itchiness; stomach pain; vomiting; trouble breathing; swelling of the face, lips, or tongue
Source: DailyMed
The following Combipatch side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common
Bloating or swelling of the face, arms, hands, lower legs, or feet
heavy non-menstrual vaginal bleeding
itching of the vagina or genital area
pain during sexual intercourse
rapid weight gain
thick, white vaginal discharge with no odor or with a mild odor
tingling of the hands or feet
unusual weight gain or loss
Incidence not known
Abdominal or stomach bloating or fullness
abdominal or stomach pain
blurred vision
change in vaginal discharge
clay-colored stools
clear or bloody discharge from the nipple
dark urine
dimpling of the breast skin
dizziness
gaseous abdominal or stomach pain
headache, severe and throbbing
hoarseness
inverted nipple
irritation
joint pain, stiffness or swelling
large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
loss of appetite
lump in the breast or under the arm
nervousness
pain or feeling of pressure in the pelvis
persistent crusting or scaling of the nipple
pounding in the ears
rash
recurrent fever
redness of the skin
redness or swelling of the breast
severe cramping of the uterus
slow or fast heartbeat
sore on the skin of the breast that does not heal
swelling of the eyelids, face, lips, hands, or feet
tightness in the chest
troubled breathing or swallowing
unpleasant breath odor
unusual tiredness or weakness
vaginal bleeding
vomiting of blood
yellow eyes or skin
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Acid or sour stomach
back pain
belching
body aches or pain
breast pain
burning, itching, redness, skin rash, swelling, or soreness at the application site
congestion
cramps
difficulty with moving
discouragement
dryness or soreness of the throat
excess air or gas in the stomach or intestines
feeling sad or empty
general feeling of discomfort or illness
headache
increased clear or white vaginal discharge
indigestion
irritability
lack or loss of strength
loss of interest or pleasure
muscle aches and pains
muscle stiffness
pain during sexual intercourse
pain or tenderness around the eyes and cheekbones
passing gas
shivering
stomach discomfort or upset
stuffy or runny nose
sweating
tender, swollen glands in the neck
thick, white vaginal discharge with no odor or with a mild odor
tiredness
trouble concentrating
trouble sleeping
Less common
Blemishes on the skin
difficulty having a bowel movement (stool)
longer or heavier menstrual periods
Incidence not known
Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
change in color of the treated skin
decreased interest in sexual intercourse
dizziness or lightheadedness
dull ache or feeling of pressure or heaviness in the legs
feeling of constant movement of self or surroundings
inability to have or keep an erection
increased in sexual ability, desire, drive, or performance
increased interest in sexual intercourse
itching skin near damaged veins
loss in sexual ability, desire, drive, or performance
sensation of spinning
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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