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Cobenfy

Cobenfy Side Effects

Robert Chad Hakim, PharmD, BCCCPDaisy Chau, PharmD
Reviewed by Robert Chad Hakim, PharmD, BCCCP, Daisy Chau, PharmD
Last reviewed on June 10, 2025

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Nausea (19%)
  • Indigestion (18%)
  • Constipation (17%)
  • Vomiting (15%)
  • High blood pressure (11%)
  • Stomach pain (8%)
  • Diarrhea (6%)

Less Common Side Effects

  • Fast heart rate
  • Dizziness
  • Acid reflux
  • Dry mouth
  • Sleepiness
  • Blurry vision
  • Too much saliva
  • Cough

Cobenfy serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Serious allergic reaction: swelling of the face, lips, tongue, or throat; trouble breathing

Source: DailyMed

The following Cobenfy side effects have also been reported

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions or angioedema—skin rash, itching or hives, swelling of the face, eyes, lips, tongue, arms, or legs, trouble swallowing or breathing
  • Anticholinergic toxicity—flushed face, blurry vision, dry mouth and skin, confusion, fast or irregular heartbeat, trouble passing urine, constipation
  • Constipation, bloating, nausea or vomiting, stomach pain, which may be signs of slow movement through the digestive tract
  • Fast or irregular heartbeat
  • Liver injury—right upper belly pain, loss of appetite, nausea, light-colored stool, dark yellow or brown urine, yellowing skin or eyes, unusual weakness or fatigue
  • Sudden eye pain or change in vision such as blurry vision, seeing halos around lights, vision loss
  • Trouble passing urine

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

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