How Much Is Clobetasol Without Insurance?

Clobetasol (Clobex, Impoyz) is a topical corticosteroid (steroid). It’s used to treat moderate-to-severe skin conditions, such as eczema, scalp psoriasis, and plaque psoriasis. It is considered “super potent” and should be used only as prescribed to limit serious side effects.

The cost of clobetasol without insurance depends on several factors, including which formulation you use and where you fill your prescription. If your insurance plan doesn’t cover clobetasol, there are ways you can save on your medication.

How much does clobetasol cost without insurance?

Without insurance, a 60 g tube of clobetasol propionate 0.05% cream can cost an average of $225.82. This is a very common dose, form, and quantity of clobetasol. But prices vary, depending on what your healthcare professional prescribes for you.

Clobetasol is available as a brand-name and generic medication. It comes in many dosage forms, including lotions, shampoos, and creams. It also comes in two formulations: clobetasol propionate and clobetasol propionate emollient. The emollient version contains ingredients that help moisturize the skin. Moisturizers can help manage symptoms of many chronic skin conditions.

The following table shows the retail price for different quantities, doses, and forms of clobetasol.

Which factors affect the cost of clobetasol?

Many factors affect the cost of clobetasol, including:

• Brand versus generic: Generic medications typically cost less than their brand-name counterparts.

• Location: GoodRx research shows that people in some cities, such as New Orleans, typically face higher prescription medication prices. Meanwhile, people in cities like Denver tend to pay below the national average.

• Pharmacy: Different pharmacies, even in the same neighborhood, may charge different prices for medications. Consider using GoodRx to compare costs at pharmacies in your area before filling your prescriptions.

• Dose, form, and quantity: Prices can vary among different medication doses and forms. And the amount you fill at one time will also affect the total cost.

• Insurance and discounts: Using insurance (if you have it) or applying discounts can help you lower your prescription costs.

Is clobetasol covered by insurance?

Many health insurance plans cover generic clobetasol. Nearly all Medicaid, Medicare, and commercial plans provide coverage, including those purchased through an Affordable Care Act (ACA) marketplace.

If you have insurance, review your plan’s summary of benefits and coverage and formulary (list of covered medications) to determine whether generic clobetasol is covered. If not, contact your prescription plan provider and ask about your coverage options.

What to do if clobetasol isn’t covered by your insurance

If your insurance doesn’t cover clobetasol, you still have options:

• If you were prescribed brand-name Clobex or Impoyz, ask your prescriber about switching to a lower-cost generic version of clobetasol.

• Use a GoodRx coupon to save on your prescription.

• Ask your prescriber about alternative topical steroids that meet your needs. Your insurance plan may offer better coverage for other medications in the same class.

• Request a formulary exception from your insurance company. If your request is denied, you have the right to file an appeal with your plan.

• When it’s time for open enrollment, compare different health insurance plans to find one that provides the coverage you need.

Ways to save on clobetasol without insurance

Whether or not you have insurance, there are ways to save on clobetasol. Here are four options to consider.

4. Tap into your HSA, FSA, or HRA

Consider using funds from a health savings account (HSA), a flexible spending account (FSA), or a health reimbursement arrangement (HRA) to purchase clobetasol. These accounts let you use pretax dollars to pay for copays, coinsurance, and other qualified medical expenses. This can help you reduce your costs through tax savings.

Just be sure to check if the money in your account has to be used before a certain time. FSA dollars have an expiration date. But HSA funds roll over and can be saved for later. HRA funds may or may not expire, depending on your account.

The bottom line

Clobetasol (Clobex, Impoyz) is a prescription-only topical corticosteroid used to treat moderate-to-severe skin conditions, such as plaque psoriasis. It’s available as a brand-name and generic medication. It also comes in several dosage forms, such as creams, ointments, and shampoos.

Without insurance, a 60 g tube of clobetasol propionate 0.05% cream can cost an average of $225.82. You could pay as little as $22.45 with a GoodRx coupon at select pharmacies in your area.

Patient assistance programs are available for people with limited incomes. Other ways to save on clobetasol include filling a 90-day supply and using funds from a tax-advantaged healthcare account.

Why trust our experts?

Written by:

Christina Aungst, PharmD

Christina Aungst, PharmD, is a pharmacy editor for GoodRx. She began writing for GoodRx Health in 2019, transitioning from freelance writer to editor in 2021.

Reviewed by:

Jennifer Gershman, PharmD, CPh, PACS

Jennifer Gershman, PharmD, is a licensed pharmacist in Florida. She has worked in the pharmacy industry for more than 15 years and is currently a medical writer.

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Methodology

We obtained national prescription coverage data for each medication from Managed Markets Insight & Technology (MMIT). The data reflects health insurance coverage as of January 2025.

We calculated the percentage of enrollees in plans that cover each medication by dividing the number of enrollees covered for the medication within a specific insurance channel (e.g., ACA, Medicare, Medicaid) by the total number of enrollees in all plans within that channel.

We determined the percentage of enrollees in plans with a prior authorization requirement by calculating the proportion of enrollees in plans that required prior authorization for the medication within each channel.

Finally, we measured the percentage of enrollees in plans with a step therapy requirement by calculating the proportion of enrollees in plans that imposed step therapy requirements for the medication in each channel.

These estimates, derived from national MMIT coverage data, provide insight into health insurance coverage for each medication. They take into account restrictions such as prior authorization, step therapy, and quantity limits. The percentages are expressed relative to the total number of enrollees covered by various insurance channels, including the ACA, commercial (excluding ACA) plans, Medicare, and Medicaid (both state-run and managed care plans).