Nitrofuran antibiotics are used to treat urinary tract infections. These medications work by interfering with the bacteria's ability to produce proteins, which stops their growth and kills them. Nitrofuran antibiotics are available in oral forms, making them easy to take. Examples include nitrofurantoin (Macrobid), nitrofurantoin macrocrystals (Macrodantin), and nitrofurantoin (Furadantin). You can take these medications as prescribed to help clear up your infection.