ACL inhibitor-cholesterol absorption inhibitor combinations are used to treat high cholesterol and to reduce the risk of heart attack, which improves overall cardiovascular health. These medications work by combining two actions: ACL inhibitors reduce cholesterol production in the liver, while cholesterol absorption inhibitors prevent cholesterol from being absorbed in the intestines. These medications are typically taken orally. An example of this combination is bempedoic acid/ezetimibe (Nexlizet). You can take these medications in pill form to help manage your cholesterol levels effectively.