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Chlordiazepoxide

Chlordiazepoxide Side Effects

Kristianne Hannemann, PharmDAllison Gourley, PharmD
Reviewed by Kristianne Hannemann, PharmD, Allison Gourley, PharmD
Last reviewed on June 6, 2023

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Drowsiness
  • Confusion
  • Loss of coordination (clumsiness)

Less Common Side Effects

  • Skin reaction
  • Fluid retention (body holds onto water)
  • Irregular periods
  • Nausea
  • Constipation
  • Movement problems
  • Change in sex drive

Chlordiazepoxide serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Severe sedation: drowsiness, slowed breathing, confusion, memory problems, slurred speech, loss of consciousness
  • Withdrawal symptoms: uncontrolled movements, blurred vision, trouble with sleep or memory, muscle pain and stiffness, vomiting, panic attacks, restlessness, irritability, hallucinations, convulsions or seizures, suicidal thoughts

Source: DailyMed

The following Chlordiazepoxide side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Rare

Fainting

mood or mental changes

shakiness and unsteady walk

unsteadiness, trembling, or other problems with muscle control or coordination

Incidence not known

Abdominal and muscle cramps

chills

clay-colored stools

convulsions

cough or hoarseness

dark urine

difficulty in speaking

dizziness

drooling

fever with or without chills

general feeling of tiredness or weakness

headache

itching

light-colored stools

loss of appetite

loss of balance control

lower back or side pain

muscle trembling, jerking, or stiffness

nausea and vomiting

painful or difficult urination

pale skin

rash

restlessness

shakiness in the legs, arms, hands, or feet

shuffling walk

sleeplessness

sore throat

sores, ulcers, or white spots on the lips or in the mouth

stiffness of the limbs

stomach pain

sweating

swelling

trouble sleeping

twisting movements of the body

unable to sleep

uncontrolled movements, especially of the face, neck, and back

unpleasant breath odor

unusual bruising or bleeding

unusual tiredness or weakness

vomiting of blood

yellow eyes or skin

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Change in consciousness

lack of coordination

loss of consciousness

sleepiness or unusual drowsiness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

Decreased interest in sexual intercourse

difficulty having a bowel movement (stool)

inability to have or keep an erection

increased in sexual ability, desire, drive, or performance

increased interest in sexual intercourse

loss in sexual ability, desire, drive, or performance

menstrual changes

skin blisters

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Why trust our experts?

Kristianne Hannemann, PharmD, is a licensed pharmacist in California. She has been a retail pharmacy manager and staff pharmacist for over 7 years and has contributed drug information content to different health companies.
Allison Gourley, PharmD, is a kidney and pancreas transplant pharmacist at a teaching hospital in the San Francisco Bay Area. When she’s not educating patients about their immunosuppressants, she's actively involved in transplant research.

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