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Estazolam

Estazolam Side Effects

Allison Gourley, PharmDDaisy Chau, PharmD
Reviewed by Allison Gourley, PharmD, Daisy Chau, PharmD
Last reviewed on July 3, 2024

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Sleepiness (42%)
  • Headache (16%)
  • Weakness (11%)
  • Slow muscle movement (8%)
  • Nervousness (8%)
  • Dizziness (7%)
  • General discomfort (5%)

Less Common Side Effects

  • Pain
  • Poor coordination
  • Muscle stiffness
  • Confusion
  • Depression
  • Abnormal thoughts
  • Abnormal dreams
  • Nausea
  • Indigestion
  • Itchiness
  • Cold symptoms

Estazolam serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Slowed brain activity: excessive sleepiness, confusion, coma
  • Trouble breathing: shallow breaths, tiredness, slow breaths
  • Dangerous sleep behaviors: sleepwalking, sleep driving, or doing any activity while not being fully alert
  • Serious allergic reaction: itchy, red rash (hives), shortness of breath, chest tightness, throat closing, nausea, vomiting, swelling of lips, tongue, face, or eyes
  • Suicidal thoughts and behavior
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Source: DailyMed

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The following Estazolam side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Absence of or decrease in body movement

clumsiness or unsteadiness

dizziness

sleepiness or unusual drowsiness

Less common

Dry mouth

false beliefs that cannot be changed by facts

headache

mood or mental changes

nausea and vomiting

poor insight and judgment

problems with memory or speech

tiredness

trouble thinking and planning

trouble walking

Rare

Aggressive or angry

blood in the urine

bloody nose

bloody, black, or tarry stools

burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

chest pain or tightness

chills

cough

crying

decrease in the amount of urine

decreased awareness or responsiveness

decreased reflexes

deep or fast breathing with dizziness

difficult urination

dryness or soreness of throat

dysphoria

fainting

false or unusual sense of well-being

fast, irregular, pounding, or racing heartbeat or pulse

fear or nervousness

feeling of unreality

feeling of warmth

fever

frequent strong or increased urge to urinate

hoarseness

increased urge to urinate during the night

irritability

lack of feeling or emotion

loss of bladder control

loss of memory

mouth sores or ulcers

muscle spasm or jerking of all extremities

noisy breathing

numbness of the feet, hands, and around mouth

paranoia

problems with memory

quick to react or overreact emotionally

rapidly changing moods

redness of the face, neck, arms, and occasionally, upper chest

restlessness

seeing, hearing, or feeling things that are not there

seizures

sense of detachment from self or body

severe sleepiness

severe stomach pain

shakiness and unsteady walk

shakiness in the legs, arms, hands, or feet

skin rash

sores, ulcers, or white spots on the lips or in the mouth

sudden loss of consciousness

swelling

swollen glands

swollen lymph nodes

trouble breathing

trouble in swallowing

trouble sleeping

uncaring

uncontrolled eye movements

unsteadiness, trembling, or other problems with muscle control or coordination

unusual bleeding or bruising

unusual tiredness or weakness

voice changes

waking to urinate at night

Incidence not known

Blistering, peeling, or loosening of the skin

diarrhea

fever with or without chills

general feeling of tiredness or weakness

itching

joint or muscle pain

lower back or side pain

muscle cramps

red, irritated eyes

red skin lesions, often with a purple center

sleeplessness

sweating

unable to sleep

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Change in consciousness

irregular, fast or slow, or shallow breathing

pale or blue lips, fingernails, or skin

slurred speech

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Lack or loss of strength

Less common

Pain in the legs or feet

Rare

Blemishes on the skin

bloated

blurred vision

burning feeling in the chest or stomach

change in color vision

change in taste bad unusual or unpleasant (after) taste

changes in vision, especially night blindness

continuing ringing or buzzing or other unexplained noise in the ears

cramping in the lower stomach, back, or legs

decreased interest in sexual intercourse

difficulty having a bowel movement (stool)

difficulty in moving

difficulty seeing at night

double vision

ear or eye pain

excess air or gas in stomach or intestines

full feeling

glare or snowy image caused by bright light

hearing loss

hives or welts

inability to have or keep an erection

increased or decreased appetite

increased sensitivity of eyes to sunlight

indigestion

loss in sexual ability, desire, drive, or performance

muscle pains or stiffness

pain in the arms, jaw, or neck

pain or tenderness around the eyes and cheekbones

pain, swelling, or redness in joints

passing gas

pimples

red, sore eyes

redness of the skin

seeing double

sneezing

stomach upset or tenderness

stuffy or runny nose

swelling of the breasts

weight gain or loss

white or brownish vaginal discharge

Incidence not known

Increased sensitivity of skin to sunlight

redness or other discoloration of skin

severe sunburn

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Why trust our experts?

Allison Gourley, PharmD, is a kidney and pancreas transplant pharmacist at a teaching hospital in the San Francisco Bay Area. When she’s not educating patients about their immunosuppressants, she's actively involved in transplant research.
Daisy Chau, PharmD
Reviewed by:
Daisy Chau, PharmD
Daisy Chau, PharmD, is the drug information pharmacist manager at GoodRx. She is licensed in California and has more than 6 years of experience working as a pharmacist in drug information.

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