Diltiazem (Cardizem) works well to treat chest pain caused by poor blood flow to the heart. Unlike its extended-release counterpart that's taken once a day, diltiazem (Cardizem) is taken four times a day. Common side effects of diltiazem (Cardizem) include swelling in the legs, dizziness, and tiredness.
Diltiazem (Cardizem) is a calcium channel blocker that slows your heart rate and relaxes your blood vessels. This gets more oxygen to the heart so it doesn't have to work as hard to pump, which relieves chest pain.
The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Contact your healthcare provider immediately if you experience any of the following.
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common
Body aches or pain
congestion
dryness or soreness of the throat
hoarseness
tender or swollen glands in the neck
trouble swallowing
voice changes
Less common
Chest pain or discomfort
chills
difficult or labored breathing
feeling faint, dizzy, or lightheaded
feeling of warmth or heat
flushing or redness of the skin, especially on the face and neck
general feeling of discomfort or illness
headache
joint pain
loss of appetite
muscle aches and pains
shivering
slow or irregular heartbeat
sweating
swelling of the hands, ankles, feet, or lower legs
tightness in the chest
trouble sleeping
unusual tiredness or weakness
vomiting
Incidence not known
Blistering, peeling, or loosening of the skin
large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
no heartbeat
red skin lesions, often with a purple center
red, irritated eyes
sores, ulcers, or white spots in the mouth or on the lips
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common
Acid or sour stomach
belching
continuing ringing or buzzing or other unexplained noise in the ears
degenerative disease of the joint
difficulty with moving
hearing loss
indigestion
lack or loss of strength
muscle aching or cramping
muscle pains or stiffness
pain or tenderness around the eyes and cheekbones
rash
stomach discomfort, upset, or pain
swollen joints
Incidence not known
Hair loss or thinning of the hair
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
In general, calcium channel blockers (CCBs), like diltiazem (Cardizem), start to work within a few hours of the first dose. But it can take up to 2 to 4 weeks to feel the full benefits of the medication. Talk with your provider about your symptoms so they can adjust your dose of diltiazem (Cardizem) accordingly. In order for diltiazem (Cardizem) to work as best as it can, make sure you take it regularly as prescribed by your provider. It's not meant to be taken only take it 'as needed' for chest pain.
No, diltiazem (Cardizem) isn't a beta blocker. Diltiazem (Cardizem) is a calcium channel blocker (CCB). In general, beta blockers and CCBs are similar in that certain medications in both classes can treat high blood pressure and chest pain. But they do so in different ways. Talk with your provider if you've more questions about how diltiazem (Cardizem) works.
People who took diltiazem (Cardizem) in clinical trials didn't report weight gain as a side effect. Talk with your provider if you've questions about diltiazem (Cardizem) and weight gain.
Yes. Though not very common, diltiazem (Cardizem) can lower your heart rate. Most of the time, you won't feel any symptoms. But if your heart rate drops too low, you might feel tired or weak. If this happens, you should get medical attention.
Yes. Dizziness is one of the more common side effects of diltiazem (Cardizem). It's most noticeable when you get up from a seated or lying down position. If dizziness continues to be an issue for you, even after you've been on the same dose for several weeks, talk with your provider.
While both diltiazem and diltiazem CD contain the same active ingredient, they don't treat the same medical conditions. Diltiazem (Cardizem) is an immediate-release version of the medication that's approved to treat chest pain (angina) only. It's taken by mouth 3 to 4 times daily. Diltiazem CD (Cardizem CD) is the extended-release version that's approved to treat both chest pain and high blood pressure (hypertension). It's taken by mouth once daily.
Diltiazem (Cardizem) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Rarely, diltiazem (Cardizem) can cause heart rhythm problems. Sometimes, this can lead to abnormally slow heart rate. Your risk of this side effect is higher if you're taking certain medications, such as digoxin or beta-blockers. Let your provider know if you feel weak or lightheaded, these might be symptoms of heart-related problems.
Diltiazem (Cardizem) can cause low blood pressure, especially if you're already taking blood pressure medications. Let your provider know right away if you experience symptoms of low blood pressure, such as dizziness, weakness, confusion, and blurry vision.
Though very rare, there have been reports of people who developed liver injury within the first 2 weeks of taking diltiazem (Cardizem). Often times, this liver damage was mild and went away on its own in 1-2 months after their provider stopped the medication. If this happens, your provider will likely monitor your liver health with blood tests.
| Dosage | Quantity | Price as low as | Price per unit |
|---|---|---|---|
| 30mg | 90 tablets | $13.00 | $0.14 |
| 60mg | 90 tablets | $13.22 | $0.15 |
| 90mg | 90 tablets | $22.32 | $0.25 |
| 120mg | 90 tablets | $13.45 | $0.15 |
The typical starting dose is 30 mg by mouth 4 times a day before meals and at bedtime. If needed, your provider will raise your dose slowly over time. The typical daily dose ranges from 180 mg to 360 mg, divided into 3 to 4 equal doses, and taken throughout the day.
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Diltiazem (Cardizem) will not be safe for you to take.