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Brexafemme
Used for Candidiasis
Used for Candidiasis
Brexafemme (ibrexafungerp) is an antifungal that's used to treat vaginal yeast infections in adults and children who've started having menstrual periods. This medication can also help lessen the risk of having a vaginal yeast infection again. In general, the dose is 2 tablets by mouth twice a day for 1 day. Side effects of Brexafemme (ibrexafungerp) include diarrhea, nausea, and stomach pain. This medication has a risk of harming an unborn baby.
What is Brexafemme (ibrexafungerp)?
What is Brexafemme (ibrexafungerp) used for?
- Treatment of vaginal yeast infection
- Lessen the occurrence of recurrent vaginal yeast infection
How Brexafemme (ibrexafungerp) works
Brexafemme (ibrexafungerp) is a triterpernoid antifungal. This type of antifungal kills the fungus that's causing the yeast infection by blocking it from making an essential protein it needs for survival.
Drug facts
| Common Brands | Brexafemme |
|---|---|
| Drug Class | Antifungal |
| Controlled Substance Classification | Not a controlled medication |
| Generic Status | No lower-cost generic available |
| Availability | Prescription only |
Side effects of Brexafemme (ibrexafungerp)
The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Diarrhea (17%)
- Nausea (12%)
- Stomach pain (11%)
Less Common Side Effects
- Dizziness
- Headache
- Vomiting
- Gas
- Back pain
- Menstrual cramps
- Vaginal bleeding
- Rash
Get your GoodRx coupon
$668.99
GoodRx discount
$557.04
Pros and cons of Brexafemme (ibrexafungerp)
Pros
- Only need to take for one day to treat vaginal yeast infection
- Only need to take once a month to help lessen recurrent infections
- Can provide symptom relief for at least 4 weeks after a dose
Cons
- Need to take twice in a day
- Can't take during pregnancy
- Need to use birth control if you can become pregnant because of the risk of harm to an unborn baby
Pharmacist tips for Brexafemme (ibrexafungerp)
- Each Brexafemme (ibrexafungerp) blister pack contains 4 tablets, which is enough medication for a one-day course of treatment.
- Take 2 tablets of Brexafemme (ibrexafungerp) by mouth in the morning and 2 tablets in the evening (about 12 hours apart). If you take the first 2 tablets in the afternoon or evening, take the other 2 tablets the next morning.
- You can take Brexafemme (ibrexafungerp) with or without food. Taking it with food can help lessen stomach upset from the medication.
- If you're able to become pregnant, be sure to use reliable birth control while you're taking Brexafemme (ibrexafungerp). Continue to use birth control for four more days after you take your last dose of the medication. This helps prevent pregnancy, which is important because the medication can cause harm to an unborn baby. Ask your primary care provider for options if you're not currently taking birth control.
- Diarrhea is a common side effect of Brexafemme (ibrexafungerp). Be sure to drink plenty of fluids if you start having diarrhea after you take this medication to prevent getting dehydrated. Speak with your primary care provider if diarrhea becomes bothersome.
- Let your healthcare team and pharmacist know what over-the-counter and prescription medications and supplements you're taking. Brexafemme (ibrexafungerp) can interact with certain medications. These interactions might make Brexafemme (ibrexafungerp) work less well for you or put you at risk for side effects. Your healthcare team can make sure all your medications are safe for you to take together.
Risks and warnings for Brexafemme (ibrexafungerp)
Brexafemme (ibrexafungerp) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Harm to an unborn baby
Brexafemme (ibrexafungerp) has the potential to cause serious harm to an unborn baby. In animal studies, Brexafemme (ibrexafungerp) caused rare birth defects and malformations. It's not known whether this risk applies to humans. But to be safe, you shouldn't take Brexafemme (ibrexafungerp) if you're pregnant.
If you can become pregnant, you'll need to take a pregnancy test before each dose of Brexafemme (ibrexafungerp). The results must be negative to make sure you're not pregnant. You'll also need to use birth control while you're taking Brexafemme (ibrexafungerp). Be sure to use birth control during the 6-month treatment period for recurrent vaginal yeast infections. Continue to use birth control for four more days after your last dose of the medication.
If you accidentally take Brexafemme (ibrexafungerp) while pregnant or find out that you're pregnant within four days of taking the medication, it's encouraged that you report your pregnancy to the manufacturer (Scynexis) at 1-888-982-7299. There's an optional pregnancy safety study that you can enroll in that monitors your health and your baby's health.
Brexafemme (ibrexafungerp) dosage
The average cost for 1 carton of 4 tablets of 150mg of Brexafemme (ibrexafungerp) is $557.04 with a free GoodRx coupon. This is 16.73% off the average retail price of $668.99. 
Carton
Carton| Dosage | Quantity | Price as low as | Price per unit |
|---|---|---|---|
| 4 tablets of 150mg | 1 carton | $557.04 | $557.04 |
Typical dosage for Brexafemme (ibrexafungerp)
Each tablet contains 150 mg of ibrexafungerp.
- Treatment of vaginal yeast infection: The typical dose is 2 tablets by mouth in the morning and 2 tablets in the evening (about 12 hours apart) for 1 day.
- Lower the risk of having a vaginal yeast infection again: The typical dose is 2 tablets by mouth in the morning and 2 tablets in the evening (about 12 hours apart) once a month for 6 months.
How much does Brexafemme (ibrexafungerp) cost?
To access savings, use a GoodRx coupon and pay just a fraction of the retail price.
Brexafemme (brand)
$557.04
Brexafemme (ibrexafungerp) contraindications
Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Brexafemme (ibrexafungerp) will not be safe for you to take.
- Currently pregnant
What are alternatives to Brexafemme (ibrexafungerp)?
There are a number of medications that your doctor can prescribe in place of Brexafemme (ibrexafungerp). Compare a few possible alternatives below.
