
Boostrix
Boostrix is a Tdap vaccine. It protects you from tetanus, diphtheria, and pertussis (also known as whooping cough). This vaccine is approved for people ages 10 years and older. It's also approved to be given during the third trimester of pregnancy to help protect the newborn baby from whooping cough. Boostrix is given as an injection into the muscle by a healthcare professional. Side effects include pain at the injection site, headache, and fatigue.
What is Boostrix?
What is Boostrix used for?
- Prevention of:
- Tetanus
- Diphtheria
- Pertussis (also known as whooping cough)
How Boostrix works
Boostrix is a type of vaccine called an inactivated vaccine. It helps protect you against infection from three bacteria that cause different conditions: tetanus, diphtheria, and pertussis (whooping cough).
The vaccine helps your body's immune system make antibodies against the bacteria. The antibodies then can attack and protect you from the bacteria if you ever get exposed to them.
Drug facts
| Common Brands | Boostrix |
|---|---|
| Drug Class | Vaccine |
| Controlled Substance Classification | Not a controlled medication |
| Generic Status | No lower-cost generic available |
| Availability | Prescription only |
Side effects of Boostrix
The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Pain at injection site (75%)
- Headache (43%)
- Tiredness (37%)
- Nausea, vomiting, diarrhea, or stomach pain (26%)
- Redness at injection site (23%)
- Swelling at injection site (21%)
- Fever (14%)
Less Common Side Effects
- Rash
- Muscle pain
Boostrix serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Serious allergic reaction: hives, rash, shaking, itching, nausea, flushing, dizziness, shortness of breath, chest pain
The following Boostrix side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur:
Less common
Collapse or shock-like state
crying for 3 hours or more
fever over 102.2 °F
redness or swelling of 4 inches or more at the injection site
seizures (convulsions)
severe pain at the injection site
Incidence not known
Agitation
back pain
black, tarry stools
bleeding gums
bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
blood in the urine or stools
bloody nose
bluish color of the fingernails, lips, skin, palms, or nail beds
blurred vision
confusion
difficulty with swallowing
dizziness
drowsiness
fast heartbeat
hallucinations
headache
hoarseness
irritability
irritation
joint pain, stiffness, or swelling
loss of bladder control
loss of consciousness
loss of strength or energy
muscle pain or weakness
pain or cramping in the abdomen or stomach
pinpoint red spots on the skin
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
rash with flat lesions or small raised lesions on the skin
screaming
shortness of breath
sleepiness or unusual drowsiness
stiff neck
swollen, painful, or tender lymph glands in the neck, armpit, or groin
tightness in the chest
total body jerking
unusual bleeding or bruising
unusual tiredness or weakness (sudden and severe)
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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Pros and cons of Boostrix
Pros
- Works well to protect you from tetanus, diphtheria, and whooping cough
- Can be given with other vaccines
Cons
- Given as an injection into the arm muscle by a healthcare professional
- Can cause pain, redness, or swelling where it's injected
Pharmacist tips for Boostrix
- Before getting Boostrix, tell the healthcare professional about your conditions and medications. They can make sure the vaccine is right for you. It might not work as well if you have certain health issues or take medications that weaken your immune system. If you have a brain problem, some side effects from Boostrix might look like your condition is getting worse.
- If you have a high fever or feel very sick on the day of your Boostrix shot, talk to a healthcare professional about waiting. Getting the vaccine when you feel better can help your body build strong protection. If you only feel mildly sick, like with a cold or low fever, you can still get Boostrix.
- The area where you got Boostrix can feel sore, get red, or be a little swollen. This is usually mild, happens a few hours after you get the shot, and goes away in a couple days. Placing a cool compress on the area and moving your arm a bit can help.
- If you have a serious or severe reaction to Boostrix, let your care team know. You can also report it to the vaccine adverse event reporting system (VAERS).
- Read the vaccine information statement for more information on Boostrix.
Risks and warnings for Boostrix
Boostrix can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Severe allergic reactions
- Risk factors: Allergic reaction to other vaccines
There's a very small chance of a severe allergic reaction after getting Boostrix. The healthcare professional might ask you to stay for a short time after to make sure you feel okay. They can get you medical care if a serious allergic reaction happens.
Sometimes, allergic reactions can happen after you go home. Get medical help right away if you notice signs of a severe allergic reaction. This can include swelling of the face, throat tightness, trouble breathing, hives, rash, dizziness, nausea, or chest pain.
If you've had a rare reaction called an Arthus reaction after a tetanus vaccine, you should wait at least 10 years before getting another Boostrix shot.
Guillain-Barré syndrome and other nerve problems
- Risk factors: Guillain-Barré syndrome within 6 weeks of receiving any tetanus vaccine
In very rare cases, some people have had nerve problems like Guillain-Barré syndrome (GBS) after getting Boostrix. This can cause nerve damage and lead to pain, muscle weakness, or even trouble moving parts of the body. Tell your primary care provider right away if you notice these symptoms after getting the vaccine.
If you had GBS within 6 weeks of getting a tetanus vaccine in the past, your risk might be higher with another dose. Before getting Boostrix, tell the healthcare professional if this has happened to you. They can make sure it's safe for you.
Lower response to Boostrix for people with a weakened immune system
- Risk factors: Medical conditions that weaken the immune system | Taking medications that lower your immune system
Boostrix might not work as well in people with a weakened immune system. They could still be at high risk of tetanus, diphtheria, and whooping cough, even after getting the vaccine.
Tell your primary care provider or healthcare professional about your conditions and medications. Some health problems can weaken your immune system. This can include human immunodeficiency virus (HIV) or cancer. Also, some medications can lower how well the immune system works. Examples are high-dose steroids and transplant medications. If this applies to you, talk to your primary care provider about staying protected.
Fainting
- Risk factors: Fainting after receiving vaccines in the past
Some people might faint after getting injectable vaccines, such as Boostrix. Signs that you might faint include blurry vision or feeling dizzy, sweaty, clammy, or weak. Tell the healthcare professional if you've fainted after getting vaccines. They can watch you closely while giving you the vaccine and right after.
Boostrix dosage
Interactions between Boostrix and other drugs
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
How much does Boostrix cost?
$48.99
Boostrix contraindications
Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Boostrix will not be safe for you to take.
- Allergy to any tetanus, diphtheria, or pertussis-containing vaccine (including DT, Td, and DTaP)
- Having brain problems within 7 days of a previous dose of a pertussis-containing vaccine. These problems can include confusion, memory loss, coma, seizures, or being less alert than usual.
What are alternatives to Boostrix?
News about Boostrix







