What is the major side effect of Januvia?

The most common Januvia side effect is cold symptoms, such as a stuffy nose and coughing. These are mild and tend to go away on their own. Headaches, low blood glucose (hypoglycemia), and joint pain are also possible. If you have heart failure or kidney problems, make sure to let your prescriber know. These can raise your risk of more serious Januvia side effects. View original source