Januvia doesn’t usually affect your kidneys. But worsening kidney function has been reported as a rare side effect. In certain people, this has progressed to acute renal failure requiring dialysis. And if you already have kidney problems, Januvia can build up in your body. This can increase the likelihood of side effects. So, certain people with existing kidney problems may need to take a lower dose and have their kidney function monitored closely while taking Januvia.
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