Is mupirocin just neosporin?

No, mupirocin is not the same as Neosporin. Neosporin is an over-the-counter topical antibiotic containing three different active ingredients: neomycin, polymyxin B, and bacitracin. It's used to prevent skin infections as minor cuts, scrapes, and burns are healing. Mupirocin is a prescription-only topical antibiotic containing a single active ingredient (mupirocin). Mupirocin can treat impetigo and bacterial skin infections that occur after skin gets damaged.