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Valacyclovir (Valtrex) is an antiviral medication. When valacyclovir (Valtrex) gets absorbed into your body, it gets converted (changed) to acyclovir, another available antiviral medication.
Valacyclovir (Valtrex) works by preventing an important protein that's used to make genetic material (DNA) from working in the herpes simplex virus and varicella zoster virus. By doing this, valacyclovir (Valtrex) prevents the virus from making copies of itself and spreading.