Zepbound is one of the most effective weight-loss medications available. During clinical trials, people using Zepbound lost an average of 15% to 21% of their starting body weight after 72 weeks (16.5 months). This worked out to an average of 34 lbs to 48 lbs. In general, people using the highest Zepbound dose (15 mg) lost more weight than those using lower doses (5 mg and 10 mg). What’s more, longer use of Zepbound can lead to even more weight loss. People in two different clinical trials saw continued weight loss with longer use — losing an average of 25% of starting body weight. Both studies ran for 72 weeks.
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