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Amitiza (lubiprostone) is a laxative used to treat chronic constipation and constipation caused by opioids. Amitiza is the only drug in the chloride channel activators class. There are currently no generic alternatives to Amitiza.
Check our savings tips for co-pay cards, assistance programs, and other ways to reduce your cost. Amitiza is covered by most Medicare and insurance plans.
Get Lubiprostone for as low as $31.26, which is 90% off the average retail price of $300.36 for the most common version, by using a GoodRx coupon.
You can save more on select medications with GoodRx Companion. See which medications are eligible.
| Dosage | Quantity | Retail price | GoodRx price |
|---|
| 8mcg | 60 capsules | $309.33 | $41.06 |
| 24mcg | 60 capsules | $309.38 | $42.03 |
250+ medications are free, with hundreds more under $10. Plans start at $9.99/mo. (when paid yearly). Terms apply.
GoodRx coupon prices last updated on 09/20/26.
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