The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
The side effects below were reported by people who used Advate during clinical trials. If you're using a product besides Advate, the side effects you experience and your risk of side effects might be different.
- Fever (16%)
- Headache (13%)
- Cough (13%)
- Sore throat, runny nose, and other symptoms of the common cold (7-12%)
Less Common Side Effects
- Joint pain
- Vomiting
- Injury in the arms or legs
- Stuffy nose
- Diarrhea
- Pain, rash, or irritation at injection site
- Ear pain, trouble hearing, and other symptoms of an ear infection
Advate serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Serious allergic reaction (anaphylaxis): difficulty breathing, hives, itching, fast heartbeat, nausea, stomach pain, dizziness, lightheadedness, swelling in the face or tongue
Source: DailyMed
The following Advate side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common
Less common or rare
Changes in facial skin color
chills
fast or irregular breathing
puffiness or swelling of the eyelids or around the eyes
sensation of burning, warmth, heat, numbness, tightness, or tingling
tightness in the chest
trouble breathing
unusual tiredness or weakness
Incidence not known
Bluish color of the fingernails, lips, skin, palms, or nail beds
blurred vision
chest pain or discomfort
confusion
deep or fast breathing with dizziness
difficult or labored breathing
difficulty with swallowing
dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
fast, pounding, or irregular heartbeat or pulse
noisy breathing
numbness of the feet, hands, and around the mouth
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
slow or irregular heartbeat
sweating
swelling of the face, throat, or tongue
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Headache
Less common
Burning, stinging, or swelling at the injection site
dizziness or lightheadedness
dry mouth or bad taste in the mouth
lack or loss of strength
nosebleed
redness of the face
vomiting
Rare
Change in taste
loss of taste
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Other Advate articles
Other Coagulation Factors side effects articles
Why trust our experts?

