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Addyi

Addyi Side Effects

Cydnee Ng, PharmDMichelle Nguyen, PharmD
Reviewed by Cydnee Ng, PharmD, Michelle Nguyen, PharmD
Last reviewed on December 15, 2025

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Dizziness (11%)
  • Sleepiness (11%)
  • Nausea (10%)
  • Tiredness (9%)
  • Trouble sleeping (5%)

Less Common Side Effects

  • Dry mouth
  • Constipation
  • Stomach pain
  • Anxiety
  • Rash

Note: Side effects were reported in premenopausal women. The percentages might be a little different for postmenopausal women.

Addyi serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Allergic reaction: swelling of the face, lips, or mouth; itchiness; hives; trouble breathing
  • Feeling faint or lightheaded

Source: Prescribing information

The following Addyi side effects have also been reported

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions or angioedema—skin rash, itching or hives, swelling of the face, eyes, lips, tongue, arms, or legs, trouble swallowing or breathing
  • CNS depression—slow or shallow breathing, shortness of breath, feeling faint, dizziness, confusion, trouble staying awake
  • Low blood pressure—dizziness, feeling faint or lightheaded, blurry vision

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

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