Key takeaways:
Pamprin products combine a few medications into one pill to treat menstrual period symptoms. They can help relieve cramps, bloating, and fatigue.
The typical Pamprin dosage is 2 caplets by mouth every 6 hours as needed. You shouldn’t take more than 8 caplets in 24 hours.
Pamprin Multi Symptom (acetaminophen/pamabrom/pyrilamine) can be used by adults and adolescents ages 12 years and older. But Pamprin Max Pain and Energy (acetaminophen/aspirin/caffeine) should only be used by adults ages 19 and older.
Pamprin products are available over the counter (OTC) as brand-name medications. But you can also find them as lower-cost generics. If your healthcare provider writes you a prescription for OTC Pamprin, GoodRx can help save you money.
Pamprin is a brand name for a line of over-the-counter (OTC) menstrual period medications. They’re popular choices for relieving symptoms like cramps and bloating. Since there are a few Pamprin products on the market, it’s important to know how to take the one you select.
To help you out, we put together a guide of typical Pamprin dosages and instructions for use.
Pamprin isn’t the name of one medication. It’s a brand name of two different OTC products. Each version contains a different combination of active ingredients. But both have a pain reliever to help with menstrual cramps and other body aches. It’s important to read the OTC “Drug Facts” label for the list of ingredients and specific instructions for use.
Pamprin Multi-Symptom comes as oral caplets. One caplet contains:
500 mg of acetaminophen (a pain reliever)
25 mg of pamabrom (a mild diuretic to help relieve bloating)
15 mg of pyrilamine maleate (an antihistamine that may help with irritability)
The adult Pamprin Multi-Symptom dosage for people age 12 and older is 2 caplets by mouth every 6 hours as needed. Don’t take more than 8 caplets in 24 hours.
Pamprin Max Pain + Energy also comes as oral caplets. One caplet contains:
250 mg of acetaminophen (a pain reliever)
250 mg of aspirin (a pain reliever)
65 mg of caffeine (to help combat fatigue and relieve bloating)
The Pamprin Max Pain + Energy dosage for adults age 19 and older is 2 caplets by mouth every 6 hours as needed. Don’t take more than 8 caplets in 24 hours.
Good to know: One dose of Pamprin Max Pain + Energy contains as much or more caffeine than a cup of coffee. It’s best to avoid taking this version of Pamprin at bedtime and limit caffeinated drinks while taking it.
Pamprin Multi-Symptom can be safely given to adolescents age 12 and older. For children younger than 12, contact their healthcare provider for recommendations to manage period symptoms.
Children and teens under 19 years old shouldn’t take Pamprin Max Pain + Energy. This is because it contains aspirin. Aspirin can cause a dangerous condition known as Reye’s syndrome in people 18 years of age and younger. Symptoms can include extreme tiredness, confusion, and seizures.
Reye’s syndrome can be life threatening. So it’s best to avoid aspirin-containing products until you’re at least 19 years old.
The Pamprin Multi-Symptom dosage for adolescents age 12 and older is the same as it is for adults. Take 2 caplets by mouth every 6 hours as needed. Don’t take more than 8 caplets in 24 hours.
While Pamprin is safe for many people to take, there are some times when you might want to avoid it. Prior to taking Pamprin products, speak to your healthcare provider or pharmacist if you:
Are taking other medications that contain acetaminophen
Have liver or kidney disease
Have high blood pressure or heart disease
Have glaucoma
Have a breathing problem, such as emphysema or chronic bronchitis
Have a condition that raises the risk of stomach bleeding, or a history of stomach bleeding from aspirin
Are taking blood thinners, diuretics, or corticosteroid medications
Are currently breastfeeding
Have had an allergic reaction to any of the ingredients in Pamprin products
Pamprin products are taken as needed for period symptoms. This means that you don’t need to worry about missed doses. Just make sure to wait at least 6 hours between each dose. Taking Pamprin sooner than this raises your risk of side effects.
Taking too much Pamprin can lead to side effects. In severe cases, it could be dangerous. Potential risks depend on the ingredients in the specific Pamprin product. But because both products contain acetaminophen, taking too much of either version can cause liver problems.
Be sure to speak to your pharmacist before combining Pamprin with other pain relief or OTC medications for period symptoms. Many products contain the same or similar ingredients as Pamprin. This could raise your risk of an unintended overdose.
If you suspect that you or someone you know has taken too much Pamprin, contact a healthcare provider, or call Poison Control at 1-800-222-1222.
There are many ways to save on Pamprin, which is available as both brand-name and generic medications. By having your healthcare provider write a prescription for OTC Pamprin, GoodRx can help you save. Generic Pamprin's price at certain pharmacies is as low as $4.83 with a free GoodRx discount.
Pamprin products combine different ingredients to treat common menstrual period symptoms. The typical Pamprin dosage is 2 caplets every 6 hours as needed. Don't take more than 8 caplets per day. Adults and adolescents aged 12 and older can take Pamprin Multi-Symptom. But Pamprin Max Pain and Energy should only be taken by adults ages 19 years and older.
Focus Consumer Healthcare, LLC. (2020). Pamprin max menstrual pain relief.
National Center for Biotechnology Information. (2023). PubChem compound summary for CID 5284451, pyrilamine maleate.
Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.