Accrufer
Accrufer (ferric maltol) is a prescription iron supplement for adults with low iron levels (iron deficiency). It comes as a 30-mg capsule that's taken by mouth twice per day on an empty stomach (1 hour before or 2 hours after a meal). Treatment typically lasts for at least 3 months, but it depends on how low your iron levels are. Side effects aren't common but can include diarrhea, constipation, discolored stool, and stomach pain.
What is Accrufer (ferric maltol)?
What is Accrufer (ferric maltol) used for?
- Iron deficiency (low iron levels with or without anemia) in adults
How Accrufer (ferric maltol) works
Accrufer (ferric maltol) is an iron supplement that helps replenish your body with iron. Iron is an important mineral for your health. Your body needs iron to make hemoglobin, a protein in your red blood cells that helps carry and deliver oxygen through your body.
Drug facts
| Common Brands | Accrufer |
|---|---|
| Drug Class | Iron supplement |
| Controlled Substance Classification | Not a controlled medication |
| Generic Status | No lower-cost generic available |
| Availability | Prescription only |
Side effects of Accrufer (ferric maltol)
The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Passing gas (5%)
Less Common Side Effects
- Diarrhea
- Constipation
- Discolored stool
- Stomach pain
- Stomach discomfort
- Nausea
- Vomiting
Accrufer (ferric maltol) serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Too much iron in the body (iron overdose): nausea, vomiting, vomiting up blood, tarry stool, stomach pain, stomach ulcer, trouble breathing, feeling confused or dizzy
More on Accrufer (ferric maltol) side effects
The following Accrufer (ferric maltol) side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
- Constipation
- Dark stools
- Metallic taste in mouth
- Nausea
- Upset stomach
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Pros and cons of Accrufer (ferric maltol)
Pros
- Starts to raise iron levels within 3 hours after you take it
- Might have a lower risk of stomach-related side effects than other iron supplements
- Taken by mouth
Cons
- Need to take twice a day on an empty stomach
- Only available as a capsule that you can't open, broken, or chew
- Hasn't been studied in children
Pharmacist tips for Accrufer (ferric maltol)
- Take Accrufer (ferric maltol) twice per day on an empty stomach, either 1 hour before or 2 hours after a meal.
- Swallow the Accrufer (ferric maltol) capsules whole. Don't open, break, or chew them. Speak with your prescriber if you're having trouble swallowing the capsules.
- Treatment with Accrufer (ferric maltol) typically lasts for at least 3 months. But your prescriber will decide how long you should take this iron supplement for based on your ferritin levels.
- Mark your calendar to get any blood tests done while you're taking Accrufer (ferric maltol). Your prescriber will keep track of your iron levels to see how well the medication is working for you.
- Stomach-related side effects like passing gas, diarrhea, and constipation are the most common side effects of Accrufer (ferric maltol). Contact a healthcare professional if these side effects are too bothersome. They can suggest treatment options that you can try.
- Accrufer (ferric maltol) make your stool discolored, which is a common side effect of iron supplements. Your stool might be a dark green or black color. Be aware that tarry, black stools can be a sign of stomach bleeding. So it's best to contact a healthcare professional if you're concerned about any changes in stool color.
- Check the labels of any other vitamins (including multivitamins) and supplements you're taking to see if they contain iron. Taking too much iron can lead to side effects, such as upset stomach, nausea, and constipation.
- Iron supplements like Accrufer (ferric maltol) can interact with many medications. Share a complete medication list with your care team. They can make sure all of your medications and over-the-counter products are safe to take together.
- Store Accrufer (ferric maltol) out of reach of children to prevent them from accidentally taking this medication. Call your local Poison Control Center right away at 1-800-222-1222 if your child accidentally took this medication, especially if they're vomiting up blood, having diarrhea, or feeling stomach pain.
More on Accrufer (ferric maltol) tips
Risks and warnings for Accrufer (ferric maltol)
Accrufer (ferric maltol) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Avoid in people having a flare-up of inflammatory bowel disease (IBD)
People currently having an IBD flare should avoid taking Accrufer (ferric maltol). The medication can worsen inflammation in the stomach lining, which can cause some blood loss. This might further lower the amount of iron in the body.
Iron overdose
- Risk factors: Taking too much iron | Receiving blood transfusions often | Medical problems that raise your blood iron level | Children under 6 years of age
Your iron level can become too high if you take multiple medications that contain iron. It can also happen if you take more Accrufer (ferric maltol) than recommended. You'll need regular blood tests so your prescriber can check that your iron levels are safe while you're taking Accrufer (ferric maltol).
Let your care team know right away if you experience any early signs of high iron levels, such as vomiting (which can include vomiting up blood), stomach pain, diarrhea, and blood in the stool. It's important to get medical help as soon as possible because high iron levels can lead to dangerous problems like tears in the gut and liver damage if not treated quickly.
Keep Accrufer (ferric maltol) out of reach of children so that they don't accidentally take it. Accidental overdose of iron-containing products can be extremely harmful to children under 6 years of age. If your child accidentally took Accrufer (ferric maltol) and they're vomiting up blood, having diarrhea, or feeling stomach pain, call your local Poison Control Center right away at 1-800-222-1222.
Accrufer (ferric maltol) dosage
| Dosage | Quantity | Price as low as | Price per unit |
|---|---|---|---|
| 30mg | 60 capsules | $199.20 | $3.32 |
Typical dosage for Accrufer (ferric maltol)
The typical dose is 30 mg by mouth twice a day on an empty stomach (1 hour before or 2 hours after a meal).
How much does Accrufer (ferric maltol) cost?
$199.20
Accrufer (ferric maltol) contraindications
Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Accrufer (ferric maltol) will not be safe for you to take.
- Medical conditions that cause high iron levels (e.g., hemochromatosis)
- Receiving many blood transfusions

